Cargando…

Triple immune modulator therapy for aberrant hyperinflammatory responses in severe COVID-19

A dysregulated hyperinflammatory response is a key pathogenesis of severe COVID-19, but optimal immune modulator treatment has not been established. To evaluate the clinical effectiveness of double (glucocorticoids and tocilizumab) and triple (plus baricitinib) immune modulator therapy for severe CO...

Descripción completa

Detalles Bibliográficos
Autores principales:	Koh, June-Young, Ko, Jae-Hoon, Lim, So Yun, Bae, Seongman, Huh, Kyungmin, Cho, Sun Young, Kang, Cheol-In, Chung, Doo Ryeon, Chung, Chi Ryang, Kim, Sung-Han, Peck, Kyong Ran, Lee, Jeong Seok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Authors. Published by Elsevier Inc. 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139747/ https://www.ncbi.nlm.nih.gov/pubmed/37119951 http://dx.doi.org/10.1016/j.clim.2023.109628

Ejemplares similares

Comparing the Synergistic and Antagonistic Interactions of Ciprofloxacin and Levofloxacin Combined with Rifampin against Drug-Resistant Staphylococcus aureus: A Time–Kill Assay
por: Kang, Yu Ri, et al.
Publicado: (2023)

Severe Thrombocytopenia in a Patient with COVID-19
por: Nham, Eliel, et al.
Publicado: (2020)

Role of echocardiography in uncomplicated Staphylococcus aureus catheter-related bloodstream infections
por: Mun, Seok Jun, et al.
Publicado: (2021)

Invasive Fungal Diseases in Kidney Transplant Recipients: Risk Factors for Mortality
por: Seok, Hyeri, et al.
Publicado: (2020)

Impact of vancomycin use trend change due to the availability of alternative antibiotics on the prevalence of Staphylococcus aureus with reduced vancomycin susceptibility: a 14-year retrospective study
por: Kang, Yu Ri, et al.
Publicado: (2022)

Difference in the Clinical Outcome of Bloodstream Infections Caused by Klebsiella aerogenes and Enterobacter cloacae Complex
por: Jeon, Minji, et al.
Publicado: (2021)

Characteristics and Clinical Outcomes of Extended-Spectrum beta-lactamase-producing Klebsiella pneumoniae Bacteremia in Cancer Patients
por: Nham, Eliel, et al.
Publicado: (2020)

1701. Differences in Diagnostic Performance of β-d-Glucan Testing in Patients with Varying Degrees of Susceptibility to Invasive Fungal Infections
por: Nham, Eliel, et al.
Publicado: (2019)

Sequence type 17 is a predictor of subsequent bacteremia in vancomycin-resistant Enterococcus faecium-colonized patients: a retrospective cohort study
por: Kim, Si-Ho, et al.
Publicado: (2021)

212. Effectiveness of Empirical Piperacillin/tazobactam Compared to Cefepime for Bloodstream Infection Caused by Gram-Negative Bacilli
por: Ho Lee, Young, et al.
Publicado: (2023)

1106. Comparison of Diagnostic Power of Conventional Culture and Automated Blood Culture System with Pleural Fluid
por: Ho Lee, Young, et al.
Publicado: (2023)

Clinical Utility of Sero-Immunological Responses Against SARS-CoV-2 Nucleocapsid Protein During Subsequent Prevalence of Wild-Type, Delta Variant, and Omicron Variant
por: Lee, Beomki, et al.
Publicado: (2023)

228. Early Recurrent Postoperative Bloodstream infections in Living-Donor Liver Transplant Recipients
por: Kim, Si-Ho, et al.
Publicado: (2019)

Clinical Features and Outcomes of Invasive Fusariosis: A Case Series in a Single Center with Literature Review
por: Kim, Ji-Yeon, et al.
Publicado: (2023)

449. Elevated Lactate Dehydrogenase in Convalescent Severe COVID-19 Patients Reflects Delayed Clinical Recovery and Activated Th(1) and Th(17) Responses
por: Yang, Jinyoung, et al.
Publicado: (2023)

Augmented humoral and cellular immunity against severe acute respiratory syndrome coronavirus 2 after breakthrough infection in kidney transplant recipients who received 3 doses of coronavirus disease 2019 vaccine
por: Yang, Jinyoung, et al.
Publicado: (2023)

Clinical application of rapid diagnostic test kit for SARS-CoV-2 antibodies into the field of patient care
por: Ko, Jae-Hoon, et al.
Publicado: (2021)

Evaluation of six anti-SARS-CoV-2 antibody test kits and practical approaches to optimize the diagnostic performance
por: Ko, Jae-Hoon, et al.
Publicado: (2021)

Poor outcomes of early recurrent post-transplant bloodstream infection in living-donor liver transplant recipients
por: Kim, Si-Ho, et al.
Publicado: (2020)

Comparison of 16S Ribosomal RNA Targeted Sequencing and Culture for Bacterial Identification in Normally Sterile Body Fluid Samples: Report of a 10-Year Clinical Laboratory Review
por: Yoo, In Young, et al.
Publicado: (2020)

Pharmacokinetic/pharmacodynamic parameters of vancomycin for predicting clinical outcome of enterococcal bacteremia
por: Nham, Eliel, et al.
Publicado: (2022)

1185. Impact of Bloodstream Infections Caused by Multidrug-resistant Organisms on Performance Status: A KARS-Net Study
por: Huh, Kyungmin, et al.
Publicado: (2018)

Modern History of Tuberculosis in Korea
por: Song, Jae-Hoon, et al.
Publicado: (2019)

Clinical Impact of Revised Ciprofloxacin Breakpoint in Patients with Urinary Tract Infections by Enterobacteriaceae
por: Park, Ga Eun, et al.
Publicado: (2021)

2149. Real-Time Nationwide Surveillance for Antimicrobial Resistance of Major Pathogens Using Automated Data Collection System in Korea: A KARS-Net Study
por: Huh, Kyungmin, et al.
Publicado: (2018)

Effect of short-term corticosteroid use on reactogenicity and immunogenicity of the first dose of ChAdOx1 nCoV-19 vaccine
por: Yang, Jinyoung, et al.
Publicado: (2021)

Effects of Short-Term Corticosteroid Use on Reactogenicity and Immunogenicity of the First Dose of ChAdOx1 nCoV-19 Vaccine
por: Yang, Jinyoung, et al.
Publicado: (2021)

Failure of Ciprofloxacin Therapy in the Treatment of Community-Acquired Acute Pyelonephritis caused by In-Vitro Susceptible Escherichia coli Strain Producing CTX-Type Extended-Spectrum β-Lactamase
por: Seok, Hyeri, et al.
Publicado: (2018)

Severity-Adjusted Dexamethasone Dosing and Tocilizumab Combination for Severe COVID-19
por: Hong, Jin Yeong, et al.
Publicado: (2022)

Estimating the Neutralizing Effect and Titer Correlation of Semi-Quantitative Anti-SARS-CoV-2 Antibody Immunoassays
por: Lee, Beomki, et al.
Publicado: (2022)

407 Impact of methicillin-resistance on mortality, hospital stay and medical cost in patients with Staphylococcus aureus bacteremia and endocarditis: A meta-analysis
por: Joo, Eun-Jeong, et al.
Publicado: (2014)

720 Clinical Features and Risk Factors for Mortality of Stenotrophomonas maltophilia Bacteremia in Patients with Hematologic Malignancies
por: Cho, Sun Young, et al.
Publicado: (2014)

Evaluation of a Carbapenem-Saving Strategy Using Empirical Combination Regimen of Piperacillin-Tazobactam and Amikacin in Hemato-Oncology Patients
por: Ko, Jae-Hoon, et al.
Publicado: (2019)

Extreme Drug Resistance in Acinetobacter baumannii Infections in Intensive Care Units, South Korea
por: Park, Young Kyoung, et al.
Publicado: (2009)

Emergence of serotype K1 Klebsiella pneumoniae ST23 strains co-producing the plasmid-mediated AmpC beta-lactamase DHA-1 and an extended-spectrum beta-lactamase in Korea
por: Cheong, Hae Suk, et al.
Publicado: (2016)

Comparison of subsequent infection in methicillin-resistant Staphylococcus aureus nasal carriers between ST72 community-genotype and hospital genotypes: a retrospective cohort study
por: Park, So Yeon, et al.
Publicado: (2017)

Clinical Significance of Non-neutropenic Fever in the Management of Diffuse Large B-Cell Lymphoma Patients Treated with Rituximab-CHOP: Comparison with Febrile Neutropenia and Risk Factor Analysis
por: Park, Silvia, et al.
Publicado: (2015)

Differential Cell Count and CRP Level in Blood as Predictors for Middle East Respiratory Syndrome Coronavirus Infection in Acute Febrile Patients during Nosocomial Outbreak
por: Park, Ga Eun, et al.
Publicado: (2017)

Clinical impact of healthcare-associated acquisition in cirrhotic patients with community-onset spontaneous bacterial peritonitis
por: Kim, Jungok, et al.
Publicado: (2020)

Effects of environmental disinfection on the isolation of vancomycin-resistant Enterococcus after a hospital-associated outbreak of Middle East respiratory syndrome
por: Ko, Jae-Hoon, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ijq5jesil9gk04m039tj703noe