Alterations of the intestinal mucus layer correlate with dysbiosis and immune dysregulation in human Type 1 Diabetes

BACKGROUND: In preclinical models of Type 1 Diabetes (T1D) the integrity of the gut barrier (GB) is instrumental to avoid dysregulated crosstalk between the commensal microbiota and immune cells and to prevent autoimmunity. The GB is composed of the intestinal epithelial barrier (IEB) and of the muc...

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Detalles Bibliográficos
Autores principales: Lo Conte, Marta, Cosorich, Ilaria, Ferrarese, Roberto, Antonini Cencicchio, Martina, Nobili, Angelica, Palmieri, Vittoria, Massimino, Luca, Lamparelli, Luigi Antonio, Liang, Wenjie, Riba, Michela, Devecchi, Elisabetta, Bolla, Andrea Mario, Pedone, Erika, Scavini, Marina, Bosi, Emanuele, Fasano, Alessio, Ungaro, Federica, Diana, Julien, Mancini, Nicasio, Falcone, Marika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139895/
https://www.ncbi.nlm.nih.gov/pubmed/37062177
http://dx.doi.org/10.1016/j.ebiom.2023.104567

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