Cargando…
Structures of an unusual 3-hydroxyacyl dehydratase (FabZ) from a ladderane-producing organism with an unexpected substrate preference
The genomes of anaerobic ammonium-oxidizing (anammox) bacteria contain a gene cluster comprising genes of unusual fatty acid biosynthesis enzymes that were suggested to be involved in the synthesis of the unique “ladderane” lipids produced by these organisms. This cluster encodes an acyl carrier pro...
Autores principales: | Dietl, Andreas, Wellach, Kathrin, Mahadevan, Pavithra, Mertes, Nicole, Winter, Sophie L., Kutsch, Tobias, Walz, Carlo, Schlichting, Ilme, Fabritz, Sebastian, Barends, Thomas R.M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139942/ https://www.ncbi.nlm.nih.gov/pubmed/36907440 http://dx.doi.org/10.1016/j.jbc.2023.104602 |
Ejemplares similares
-
Crystal structure of FabZ-ACP complex reveals a dynamic seesaw-like catalytic mechanism of dehydratase in fatty acid biosynthesis
por: Zhang, Lin, et al.
Publicado: (2016) -
Functions of the Clostridium acetobutylicium FabF and FabZ proteins in unsaturated fatty acid biosynthesis
por: Zhu, Lei, et al.
Publicado: (2009) -
The Role of Type II Fatty Acid Synthesis Enzymes FabZ, ODSCI, and ODSCII in the Pathogenesis of Toxoplasma gondii Infection
por: Xu, Xiao-Pei, et al.
Publicado: (2021) -
Identification and Phenotypic Characterization of ZEBRA LEAF16 Encoding a β-Hydroxyacyl-ACP Dehydratase in Rice
por: Liu, Ziwen, et al.
Publicado: (2018) -
Molecular basis for the inhibition of β-hydroxyacyl-ACP dehydratase HadAB complex from Mycobacterium tuberculosis by flavonoid inhibitors
por: Dong, Yu, et al.
Publicado: (2015)