Pleuroparenchymal fibroelastosis secondary to autologous peripheral blood stem cell transplantation: A case report

Pleuroparenchymal fibroelastosis (PPFE) is a rare form of interstitial pneumonitis. Although most cases of PPFE are idiopathic, some cases of PPFE occur secondary to stem cell transplantation. We report a 41-year-old woman developed pneumonia after autologous peripheral blood system cell transplanta...

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Detalles Bibliográficos
Autores principales: Egashira, Ayaka, Yoneshima, Yasuto, Mizusaki, Shun, Tsuneoka, Yuki, Tsubouchi, Kazuya, Okamoto, Isamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139946/
https://www.ncbi.nlm.nih.gov/pubmed/37124056
http://dx.doi.org/10.1016/j.rmcr.2023.101845
Descripción
Sumario:Pleuroparenchymal fibroelastosis (PPFE) is a rare form of interstitial pneumonitis. Although most cases of PPFE are idiopathic, some cases of PPFE occur secondary to stem cell transplantation. We report a 41-year-old woman developed pneumonia after autologous peripheral blood system cell transplantation (PBSCT). Eleven years after PBSCT, she presented with dyspnea. A computed tomographic scan showed pleuroparenchymal thickening and predominantly in the upper lobes. She was diagnosed with PPFE secondary to PBSCT. She was started nintedanib and administered oxygen therapy. Most cases of PPFE secondary to stem cell transplantation have been reported. However, we experienced the case of PPFE post-autologous PBSCT.

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