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Marginal zone B cells are responsible for the production of alloantibodies following platelet transfusion in mice
Alloimmunization against platelets remains a potentially serious adverse transfusion event. Alloantibodies produced by the recipient, mainly directed against human leukocyte antigen class I donor antigens, can compromise the therapeutic efficacy of subsequent transfusions, and may lead to refractori...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society of Hematology
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139948/ https://www.ncbi.nlm.nih.gov/pubmed/36490266 http://dx.doi.org/10.1182/bloodadvances.2022008411 |