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A five-safes approach to a secure and scalable genomics data repository
Genomic researchers increasingly utilize commercial cloud service providers (CSPs) to manage data and analytics needs. CSPs allow researchers to grow Information Technology (IT) infrastructure on demand to overcome bottlenecks when combining large datasets. However, without adequate security control...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139958/ https://www.ncbi.nlm.nih.gov/pubmed/37123247 http://dx.doi.org/10.1016/j.isci.2023.106546 |
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author | Shih, Chih Chuan Chen, Jieqi Lee, Ai Shan Bertin, Nicolas Hebrard, Maxime Khor, Chiea Chuen Li, Zheng Juan Tan, Joanna Hui Meah, Wee Yang Peh, Su Qin Mok, Shi Qi Sim, Kar Seng Liu, Jianjun Wang, Ling Wong, Eleanor Li, Jingmei Tin, Aung Cheng, Ching-Yu Heng, Chew-Kiat Yuan, Jian-Min Koh, Woon-Puay Saw, Seang Mei Friedlander, Yechiel Sim, Xueling Chai, Jin Fang Chong, Yap Seng Davila, Sonia Goh, Liuh Ling Lee, Eng Sing Wong, Tien Yin Karnani, Neerja Leong, Khai Pang Yeo, Khung Keong Chambers, John C. Lim, Su Chi Goh, Rick Siow Mong Tan, Patrick Dorajoo, Rajkumar |
author_facet | Shih, Chih Chuan Chen, Jieqi Lee, Ai Shan Bertin, Nicolas Hebrard, Maxime Khor, Chiea Chuen Li, Zheng Juan Tan, Joanna Hui Meah, Wee Yang Peh, Su Qin Mok, Shi Qi Sim, Kar Seng Liu, Jianjun Wang, Ling Wong, Eleanor Li, Jingmei Tin, Aung Cheng, Ching-Yu Heng, Chew-Kiat Yuan, Jian-Min Koh, Woon-Puay Saw, Seang Mei Friedlander, Yechiel Sim, Xueling Chai, Jin Fang Chong, Yap Seng Davila, Sonia Goh, Liuh Ling Lee, Eng Sing Wong, Tien Yin Karnani, Neerja Leong, Khai Pang Yeo, Khung Keong Chambers, John C. Lim, Su Chi Goh, Rick Siow Mong Tan, Patrick Dorajoo, Rajkumar |
author_sort | Shih, Chih Chuan |
collection | PubMed |
description | Genomic researchers increasingly utilize commercial cloud service providers (CSPs) to manage data and analytics needs. CSPs allow researchers to grow Information Technology (IT) infrastructure on demand to overcome bottlenecks when combining large datasets. However, without adequate security controls, the risk of unauthorized access may be higher for data stored on the cloud. Additionally, regulators are mandating data access patterns and specific security protocols for the storage and use of genomic data. While CSP provides tools for security and regulatory compliance, building the necessary controls required for cloud solutions is not trivial. Research Assets Provisioning and Tracking Online Repository (RAPTOR) by the Genome Institute of Singapore is a cloud-native genomics data repository and analytics platform that implements a “five-safes” framework to provide security and governance controls to data contributors and users, leveraging CSP for sharing and analysis of genomic datasets without the risk of security breaches or running afoul of regulations. |
format | Online Article Text |
id | pubmed-10139958 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-101399582023-04-29 A five-safes approach to a secure and scalable genomics data repository Shih, Chih Chuan Chen, Jieqi Lee, Ai Shan Bertin, Nicolas Hebrard, Maxime Khor, Chiea Chuen Li, Zheng Juan Tan, Joanna Hui Meah, Wee Yang Peh, Su Qin Mok, Shi Qi Sim, Kar Seng Liu, Jianjun Wang, Ling Wong, Eleanor Li, Jingmei Tin, Aung Cheng, Ching-Yu Heng, Chew-Kiat Yuan, Jian-Min Koh, Woon-Puay Saw, Seang Mei Friedlander, Yechiel Sim, Xueling Chai, Jin Fang Chong, Yap Seng Davila, Sonia Goh, Liuh Ling Lee, Eng Sing Wong, Tien Yin Karnani, Neerja Leong, Khai Pang Yeo, Khung Keong Chambers, John C. Lim, Su Chi Goh, Rick Siow Mong Tan, Patrick Dorajoo, Rajkumar iScience Article Genomic researchers increasingly utilize commercial cloud service providers (CSPs) to manage data and analytics needs. CSPs allow researchers to grow Information Technology (IT) infrastructure on demand to overcome bottlenecks when combining large datasets. However, without adequate security controls, the risk of unauthorized access may be higher for data stored on the cloud. Additionally, regulators are mandating data access patterns and specific security protocols for the storage and use of genomic data. While CSP provides tools for security and regulatory compliance, building the necessary controls required for cloud solutions is not trivial. Research Assets Provisioning and Tracking Online Repository (RAPTOR) by the Genome Institute of Singapore is a cloud-native genomics data repository and analytics platform that implements a “five-safes” framework to provide security and governance controls to data contributors and users, leveraging CSP for sharing and analysis of genomic datasets without the risk of security breaches or running afoul of regulations. Elsevier 2023-03-31 /pmc/articles/PMC10139958/ /pubmed/37123247 http://dx.doi.org/10.1016/j.isci.2023.106546 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Shih, Chih Chuan Chen, Jieqi Lee, Ai Shan Bertin, Nicolas Hebrard, Maxime Khor, Chiea Chuen Li, Zheng Juan Tan, Joanna Hui Meah, Wee Yang Peh, Su Qin Mok, Shi Qi Sim, Kar Seng Liu, Jianjun Wang, Ling Wong, Eleanor Li, Jingmei Tin, Aung Cheng, Ching-Yu Heng, Chew-Kiat Yuan, Jian-Min Koh, Woon-Puay Saw, Seang Mei Friedlander, Yechiel Sim, Xueling Chai, Jin Fang Chong, Yap Seng Davila, Sonia Goh, Liuh Ling Lee, Eng Sing Wong, Tien Yin Karnani, Neerja Leong, Khai Pang Yeo, Khung Keong Chambers, John C. Lim, Su Chi Goh, Rick Siow Mong Tan, Patrick Dorajoo, Rajkumar A five-safes approach to a secure and scalable genomics data repository |
title | A five-safes approach to a secure and scalable genomics data repository |
title_full | A five-safes approach to a secure and scalable genomics data repository |
title_fullStr | A five-safes approach to a secure and scalable genomics data repository |
title_full_unstemmed | A five-safes approach to a secure and scalable genomics data repository |
title_short | A five-safes approach to a secure and scalable genomics data repository |
title_sort | five-safes approach to a secure and scalable genomics data repository |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139958/ https://www.ncbi.nlm.nih.gov/pubmed/37123247 http://dx.doi.org/10.1016/j.isci.2023.106546 |
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