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Characterization of a polyclonal antibody that is highly selective for the d-isoAsp-25 variant of mammalian histone H2B
Approximately 12% of histone H2B molecules in mammalian brain contain a modification wherein Asp25 is present as the d-enantiomer, and is mostly linked to Gly26 via the side-chain carboxyl. Here we (1) demonstrate the high specificity of a polyclonal antibody to this modification, and (2) use this A...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Vienna
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140013/ https://www.ncbi.nlm.nih.gov/pubmed/36717395 http://dx.doi.org/10.1007/s00726-023-03242-z |