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Automated design of protein-binding riboswitches for sensing human biomarkers in a cell-free expression system
Cell-free genetically encoded biosensors have been developed to detect small molecules and nucleic acids, but they have yet to be reliably engineered to detect proteins. Here we develop an automated platform to convert protein-binding RNA aptamers into riboswitch sensors that operate within low-cost...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140043/ https://www.ncbi.nlm.nih.gov/pubmed/37105971 http://dx.doi.org/10.1038/s41467-023-38098-0 |