Cargando…
Magnetic resonance imaging at 9.4 T: the Maastricht journey
The 9.4 T scanner in Maastricht is a whole-body magnet with head gradients and parallel RF transmit capability. At the time of the design, it was conceptualized to be one of the best fMRI scanners in the world, but it has also been used for anatomical and diffusion imaging. 9.4 T offers increases in...
Autores principales: | , , , , , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140139/ https://www.ncbi.nlm.nih.gov/pubmed/37081247 http://dx.doi.org/10.1007/s10334-023-01080-4 |
_version_ | 1785033100012552192 |
---|---|
author | Ivanov, Dimo De Martino, Federico Formisano, Elia Fritz, Francisco J. Goebel, Rainer Huber, Laurentius Kashyap, Sriranga Kemper, Valentin G. Kurban, Denizhan Roebroeck, Alard Sengupta, Shubharthi Sorger, Bettina Tse, Desmond H. Y. Uludağ, Kâmil Wiggins, Christopher J. Poser, Benedikt A. |
author_facet | Ivanov, Dimo De Martino, Federico Formisano, Elia Fritz, Francisco J. Goebel, Rainer Huber, Laurentius Kashyap, Sriranga Kemper, Valentin G. Kurban, Denizhan Roebroeck, Alard Sengupta, Shubharthi Sorger, Bettina Tse, Desmond H. Y. Uludağ, Kâmil Wiggins, Christopher J. Poser, Benedikt A. |
author_sort | Ivanov, Dimo |
collection | PubMed |
description | The 9.4 T scanner in Maastricht is a whole-body magnet with head gradients and parallel RF transmit capability. At the time of the design, it was conceptualized to be one of the best fMRI scanners in the world, but it has also been used for anatomical and diffusion imaging. 9.4 T offers increases in sensitivity and contrast, but the technical ultra-high field (UHF) challenges, such as field inhomogeneities and constraints set by RF power deposition, are exacerbated compared to 7 T. This article reviews some of the 9.4 T work done in Maastricht. Functional imaging experiments included blood oxygenation level-dependent (BOLD) and blood-volume weighted (VASO) fMRI using different readouts. BOLD benefits from shorter T(2)* at 9.4 T while VASO from longer T(1). We show examples of both ex vivo and in vivo anatomical imaging. For many applications, pTx and optimized coils are essential to harness the full potential of 9.4 T. Our experience shows that, while considerable effort was required compared to our 7 T scanner, we could obtain high-quality anatomical and functional data, which illustrates the potential of MR acquisitions at even higher field strengths. The practical challenges of working with a relatively unique system are also discussed. |
format | Online Article Text |
id | pubmed-10140139 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-101401392023-04-29 Magnetic resonance imaging at 9.4 T: the Maastricht journey Ivanov, Dimo De Martino, Federico Formisano, Elia Fritz, Francisco J. Goebel, Rainer Huber, Laurentius Kashyap, Sriranga Kemper, Valentin G. Kurban, Denizhan Roebroeck, Alard Sengupta, Shubharthi Sorger, Bettina Tse, Desmond H. Y. Uludağ, Kâmil Wiggins, Christopher J. Poser, Benedikt A. MAGMA Review The 9.4 T scanner in Maastricht is a whole-body magnet with head gradients and parallel RF transmit capability. At the time of the design, it was conceptualized to be one of the best fMRI scanners in the world, but it has also been used for anatomical and diffusion imaging. 9.4 T offers increases in sensitivity and contrast, but the technical ultra-high field (UHF) challenges, such as field inhomogeneities and constraints set by RF power deposition, are exacerbated compared to 7 T. This article reviews some of the 9.4 T work done in Maastricht. Functional imaging experiments included blood oxygenation level-dependent (BOLD) and blood-volume weighted (VASO) fMRI using different readouts. BOLD benefits from shorter T(2)* at 9.4 T while VASO from longer T(1). We show examples of both ex vivo and in vivo anatomical imaging. For many applications, pTx and optimized coils are essential to harness the full potential of 9.4 T. Our experience shows that, while considerable effort was required compared to our 7 T scanner, we could obtain high-quality anatomical and functional data, which illustrates the potential of MR acquisitions at even higher field strengths. The practical challenges of working with a relatively unique system are also discussed. Springer International Publishing 2023-04-20 2023 /pmc/articles/PMC10140139/ /pubmed/37081247 http://dx.doi.org/10.1007/s10334-023-01080-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Review Ivanov, Dimo De Martino, Federico Formisano, Elia Fritz, Francisco J. Goebel, Rainer Huber, Laurentius Kashyap, Sriranga Kemper, Valentin G. Kurban, Denizhan Roebroeck, Alard Sengupta, Shubharthi Sorger, Bettina Tse, Desmond H. Y. Uludağ, Kâmil Wiggins, Christopher J. Poser, Benedikt A. Magnetic resonance imaging at 9.4 T: the Maastricht journey |
title | Magnetic resonance imaging at 9.4 T: the Maastricht journey |
title_full | Magnetic resonance imaging at 9.4 T: the Maastricht journey |
title_fullStr | Magnetic resonance imaging at 9.4 T: the Maastricht journey |
title_full_unstemmed | Magnetic resonance imaging at 9.4 T: the Maastricht journey |
title_short | Magnetic resonance imaging at 9.4 T: the Maastricht journey |
title_sort | magnetic resonance imaging at 9.4 t: the maastricht journey |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140139/ https://www.ncbi.nlm.nih.gov/pubmed/37081247 http://dx.doi.org/10.1007/s10334-023-01080-4 |
work_keys_str_mv | AT ivanovdimo magneticresonanceimagingat94tthemaastrichtjourney AT demartinofederico magneticresonanceimagingat94tthemaastrichtjourney AT formisanoelia magneticresonanceimagingat94tthemaastrichtjourney AT fritzfranciscoj magneticresonanceimagingat94tthemaastrichtjourney AT goebelrainer magneticresonanceimagingat94tthemaastrichtjourney AT huberlaurentius magneticresonanceimagingat94tthemaastrichtjourney AT kashyapsriranga magneticresonanceimagingat94tthemaastrichtjourney AT kempervalenting magneticresonanceimagingat94tthemaastrichtjourney AT kurbandenizhan magneticresonanceimagingat94tthemaastrichtjourney AT roebroeckalard magneticresonanceimagingat94tthemaastrichtjourney AT senguptashubharthi magneticresonanceimagingat94tthemaastrichtjourney AT sorgerbettina magneticresonanceimagingat94tthemaastrichtjourney AT tsedesmondhy magneticresonanceimagingat94tthemaastrichtjourney AT uludagkamil magneticresonanceimagingat94tthemaastrichtjourney AT wigginschristopherj magneticresonanceimagingat94tthemaastrichtjourney AT poserbenedikta magneticresonanceimagingat94tthemaastrichtjourney |