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Structural basis for reduced ribosomal A-site fidelity in response to P-site codon–anticodon mismatches

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Rapid and accurate translation is essential in all organisms to produce properly folded and functional proteins. mRNA codons that define the protein-coding sequences are decoded by tRNAs on the ribosome in the aminoacyl (A) binding site. The mRNA codon and the tRNA anticodon interaction is extensive...

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Detalles Bibliográficos
Autores principales:	Nguyen, Ha An, Hoffer, Eric D., Fagan, Crystal E., Maehigashi, Tatsuya, Dunham, Christine M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140155/ https://www.ncbi.nlm.nih.gov/pubmed/36924943 http://dx.doi.org/10.1016/j.jbc.2023.104608

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