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Structural basis for reduced ribosomal A-site fidelity in response to P-site codon–anticodon mismatches
Rapid and accurate translation is essential in all organisms to produce properly folded and functional proteins. mRNA codons that define the protein-coding sequences are decoded by tRNAs on the ribosome in the aminoacyl (A) binding site. The mRNA codon and the tRNA anticodon interaction is extensive...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140155/ https://www.ncbi.nlm.nih.gov/pubmed/36924943 http://dx.doi.org/10.1016/j.jbc.2023.104608 |
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