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Molecular determinants for differential activation of the bile acid receptor from the pathogen Vibrio parahaemolyticus

Bile acids are important for digestion of food and antimicrobial activity. Pathogenic Vibrio parahaemolyticus senses bile acids and induce pathogenesis. The bile acid taurodeoxycholate (TDC) was shown to activate the master regulator, VtrB, of this system, whereas other bile acids such as chenodeoxy...

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Detalles Bibliográficos
Autores principales: Zou, Angela J., Kinch, Lisa, Chimalapati, Suneeta, Garcia, Nalleli, Tomchick, Diana R., Orth, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140157/
https://www.ncbi.nlm.nih.gov/pubmed/36894018
http://dx.doi.org/10.1016/j.jbc.2023.104591

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