HMGN1 enhances CRISPR-directed dual-function A-to-G and C-to-G base editing

C-to-G base editors have been successfully constructed recently, but limited work has been done on concurrent C-to-G and A-to-G base editing. In addition, there is also limited data on how chromatin-associated factors affect the base editing. Here, we test a series of chromatin-associated factors, a...

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Detalles Bibliográficos
Autores principales: Yang, Chao, Ma, Zhenzhen, Wang, Keshan, Dong, Xingxiao, Huang, Meiyu, Li, Yaqiu, Zhu, Xiagu, Li, Ju, Cheng, Zhihui, Bi, Changhao, Zhang, Xueli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140177/
https://www.ncbi.nlm.nih.gov/pubmed/37105976
http://dx.doi.org/10.1038/s41467-023-38193-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140177/
https://www.ncbi.nlm.nih.gov/pubmed/37105976
http://dx.doi.org/10.1038/s41467-023-38193-2

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