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HMGN1 enhances CRISPR-directed dual-function A-to-G and C-to-G base editing
C-to-G base editors have been successfully constructed recently, but limited work has been done on concurrent C-to-G and A-to-G base editing. In addition, there is also limited data on how chromatin-associated factors affect the base editing. Here, we test a series of chromatin-associated factors, a...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140177/ https://www.ncbi.nlm.nih.gov/pubmed/37105976 http://dx.doi.org/10.1038/s41467-023-38193-2 |