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Construction of cancer- associated fibroblasts related risk signature based on single-cell RNA-seq and bulk RNA-seq data in bladder urothelial carcinoma

BACKGROUND: The ability of cancer-associated fibroblasts (CAFs) to encourage angiogenesis, tumor cell spread, and increase treatment resistance makes them pro-tumorigenic. We aimed to investigate the CAF signature in Bladder urothelial carcinoma (BLCA) and, for clinical application, to build a CAF-b...

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Detalles Bibliográficos
Autores principales:	Liu, Yunxun, Jian, Jun, Zhang, Ye, Wang, Lei, Liu, Xiuheng, Chen, Zhiyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140328/ https://www.ncbi.nlm.nih.gov/pubmed/37124542 http://dx.doi.org/10.3389/fonc.2023.1170893

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