Tuning the immune response: sulfated archaeal glycolipid archaeosomes as an effective vaccine adjuvant for induction of humoral and cell-mediated immunity towards the SARS-CoV-2 Omicron variant of concern

Liposomes composed of sulfated lactosyl archaeol (SLA) have been shown to be a safe and effective vaccine adjuvant with a multitude of antigens in preclinical studies. In particular, SLA-adjuvanted SARS-CoV-2 subunit vaccines based on trimeric spike protein antigens were shown to be immunogenic and...

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Detalles Bibliográficos
Autores principales: Renner, Tyler M., Akache, Bassel, Stuible, Matthew, Rohani, Nazanin, Cepero-Donates, Yuneivy, Deschatelets, Lise, Dudani, Renu, Harrison, Blair A., Baardsnes, Jason, Koyuturk, Izel, Hill, Jennifer J., Hemraz, Usha D., Régnier, Sophie, Lenferink, Anne E. G., Durocher, Yves, McCluskie, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140330/
https://www.ncbi.nlm.nih.gov/pubmed/37122746
http://dx.doi.org/10.3389/fimmu.2023.1182556

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