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TIGAR deficiency induces caspase-1-dependent trophoblasts pyroptosis through NLRP3-ASC inflammasome

INTRODUCTION: Gestational diabetes mellitus (GDM), a common complication of pregnancy, is risky for both mother and fetus. Previous studies about TP53-induced glycolysis and apoptosis regulator (TIGAR) focused on the occurrence and development of cancer, cardiovascular disease, and neurological dise...

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Detalles Bibliográficos
Autores principales:	Guo, Junjun, Zhou, Meijuan, Zhao, Man, Li, Shuxian, Fang, Zhenya, Li, Anna, Zhang, Meihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140348/ https://www.ncbi.nlm.nih.gov/pubmed/37122710 http://dx.doi.org/10.3389/fimmu.2023.1114620

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