Spatial transcriptomics reveals the heterogeneity and FGG+CRP+ inflammatory cancer-associated fibroblasts replace islets in pancreatic ductal adenocarcinoma

BACKGROUND: Understanding the spatial heterogeneity of the tumor microenvironment (TME) in pancreatic cancer (PC) remains challenging. METHODS: In this study, we performed spatial transcriptomics (ST) to investigate the gene expression features across one normal pancreatic tissue, PC tissue, adjacen...

Descripción completa

Detalles Bibliográficos
Autores principales: Ren, Zhangyong, Pan, Bing, Wang, Fangfei, Lyu, Shaocheng, Zhai, Jialei, Hu, Xiumei, Liu, Zhe, Li, Lixin, Lang, Ren, He, Qiang, Zhao, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140349/
https://www.ncbi.nlm.nih.gov/pubmed/37124494
http://dx.doi.org/10.3389/fonc.2023.1112576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140349/
https://www.ncbi.nlm.nih.gov/pubmed/37124494
http://dx.doi.org/10.3389/fonc.2023.1112576

Ejemplares similares