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T cell biomarkers come to the fore in cancer immunotherapy

A comprehensive study by van der Sluis et al.(1) demonstrates immunotherapeutic targeting of OX40 and PD-L1 results in enhanced tumor clearance, which is linked to the dynamic emergence of distinct subsets of CD8(+) T cells.

Detalles Bibliográficos
Autores principales: Sheriff, Lozan, Copland, Alastair, Bending, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140386/
https://www.ncbi.nlm.nih.gov/pubmed/37001529
http://dx.doi.org/10.1016/j.xcrm.2023.100989
Descripción
Sumario:A comprehensive study by van der Sluis et al.(1) demonstrates immunotherapeutic targeting of OX40 and PD-L1 results in enhanced tumor clearance, which is linked to the dynamic emergence of distinct subsets of CD8(+) T cells.