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The effect of orthokeratology lenses on optical quality and visual function in children

PURPOSE: To assess changes in optical quality and visual function in children after 3 months of wearing orthokeratology (OK) lenses. METHODS: A total of 25 myopic children aged 8–12 years were recruited and completed the follow-up study. Optical quality, visual function and corneal morphology were a...

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Autores principales: Lu, Weiwei, Song, Guanxin, Zhang, Yuhan, Lian, Yan, Ma, Ke, Lu, Qingqing, Jin, Yiyu, Zhao, Yang, Zhang, Shuyu, Lv, Fan, Jin, Wanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140410/
https://www.ncbi.nlm.nih.gov/pubmed/37123367
http://dx.doi.org/10.3389/fnins.2023.1142524
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author Lu, Weiwei
Song, Guanxin
Zhang, Yuhan
Lian, Yan
Ma, Ke
Lu, Qingqing
Jin, Yiyu
Zhao, Yang
Zhang, Shuyu
Lv, Fan
Jin, Wanqing
author_facet Lu, Weiwei
Song, Guanxin
Zhang, Yuhan
Lian, Yan
Ma, Ke
Lu, Qingqing
Jin, Yiyu
Zhao, Yang
Zhang, Shuyu
Lv, Fan
Jin, Wanqing
author_sort Lu, Weiwei
collection PubMed
description PURPOSE: To assess changes in optical quality and visual function in children after 3 months of wearing orthokeratology (OK) lenses. METHODS: A total of 25 myopic children aged 8–12 years were recruited and completed the follow-up study. Optical quality, visual function and corneal morphology were assessed at baseline and at follow-ups 1 and 3 months after wearing OK lenses. Optical quality parameters mainly included the modulation transfer function (MTF) cutoff, objective scattering index (OSI), Strehl ratio (SR) and the predicted visual acuities (PVAs). Visual function was assessed by visual acuity, monocular contrast sensitivity function (CSF) across five spatial frequencies and the area under the log contrast sensitivity function (AULCSF) that was also computed as an index for overall CSF. RESULTS: The MTF cutoff and SR values both increased after 1 month of wearing the OK lenses (baseline vs. 1 month: P(MTF) = 0.008 and P(SR) = 0.049); this improvement plateaued after 3 months of lens wear (1 month vs. 3 months: P(MTF) = 0.626, P(SR) = 0.428). The corneal morphology also showed the similar change trend. The OSI showed the opposite change trend (baseline vs. 1 month: P(OSI) < 0.001; 1 month vs. 3 months: P(OSI) = 0.720). The mean CSF at 1.5 cpd decreased significantly after 1 month of wearing the lenses (baseline vs. 1 month: p = 0.001) and recovered after 3 months of lens wear (baseline vs. 3 months: p = 0.076). CSF at spatial frequencies of 3, 6, 12 and 18 cpd as well as the AULCSF did not significantly differ between any two timepoints (all Ps > 0.05). CONCLUSION: After 3 months of wearing OK lenses, the subjects exhibited a decrease in optical quality, similar to corneal morphology, whereas their visual function remained largely unchanged. Thus, the optical quality was more susceptible to OK lenses than visual function in children. The initial month of OK treatment of children is a key period to be paid close attention to deterioration of optical quality and visual function.
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spelling pubmed-101404102023-04-29 The effect of orthokeratology lenses on optical quality and visual function in children Lu, Weiwei Song, Guanxin Zhang, Yuhan Lian, Yan Ma, Ke Lu, Qingqing Jin, Yiyu Zhao, Yang Zhang, Shuyu Lv, Fan Jin, Wanqing Front Neurosci Neuroscience PURPOSE: To assess changes in optical quality and visual function in children after 3 months of wearing orthokeratology (OK) lenses. METHODS: A total of 25 myopic children aged 8–12 years were recruited and completed the follow-up study. Optical quality, visual function and corneal morphology were assessed at baseline and at follow-ups 1 and 3 months after wearing OK lenses. Optical quality parameters mainly included the modulation transfer function (MTF) cutoff, objective scattering index (OSI), Strehl ratio (SR) and the predicted visual acuities (PVAs). Visual function was assessed by visual acuity, monocular contrast sensitivity function (CSF) across five spatial frequencies and the area under the log contrast sensitivity function (AULCSF) that was also computed as an index for overall CSF. RESULTS: The MTF cutoff and SR values both increased after 1 month of wearing the OK lenses (baseline vs. 1 month: P(MTF) = 0.008 and P(SR) = 0.049); this improvement plateaued after 3 months of lens wear (1 month vs. 3 months: P(MTF) = 0.626, P(SR) = 0.428). The corneal morphology also showed the similar change trend. The OSI showed the opposite change trend (baseline vs. 1 month: P(OSI) < 0.001; 1 month vs. 3 months: P(OSI) = 0.720). The mean CSF at 1.5 cpd decreased significantly after 1 month of wearing the lenses (baseline vs. 1 month: p = 0.001) and recovered after 3 months of lens wear (baseline vs. 3 months: p = 0.076). CSF at spatial frequencies of 3, 6, 12 and 18 cpd as well as the AULCSF did not significantly differ between any two timepoints (all Ps > 0.05). CONCLUSION: After 3 months of wearing OK lenses, the subjects exhibited a decrease in optical quality, similar to corneal morphology, whereas their visual function remained largely unchanged. Thus, the optical quality was more susceptible to OK lenses than visual function in children. The initial month of OK treatment of children is a key period to be paid close attention to deterioration of optical quality and visual function. Frontiers Media S.A. 2023-04-14 /pmc/articles/PMC10140410/ /pubmed/37123367 http://dx.doi.org/10.3389/fnins.2023.1142524 Text en Copyright © 2023 Lu, Song, Zhang, Lian, Ma, Lu, Jin, Zhao, Zhang, Lv and Jin. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Lu, Weiwei
Song, Guanxin
Zhang, Yuhan
Lian, Yan
Ma, Ke
Lu, Qingqing
Jin, Yiyu
Zhao, Yang
Zhang, Shuyu
Lv, Fan
Jin, Wanqing
The effect of orthokeratology lenses on optical quality and visual function in children
title The effect of orthokeratology lenses on optical quality and visual function in children
title_full The effect of orthokeratology lenses on optical quality and visual function in children
title_fullStr The effect of orthokeratology lenses on optical quality and visual function in children
title_full_unstemmed The effect of orthokeratology lenses on optical quality and visual function in children
title_short The effect of orthokeratology lenses on optical quality and visual function in children
title_sort effect of orthokeratology lenses on optical quality and visual function in children
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140410/
https://www.ncbi.nlm.nih.gov/pubmed/37123367
http://dx.doi.org/10.3389/fnins.2023.1142524
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