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Planning, implementation, and sustaining high coverage of human papillomavirus (HPV) vaccination programs: What works in the context of low-resource countries?

Cervical cancer due to human papillomavirus (HPV) infection is a leading cause of mortality among women in low-resource settings. Many Sub-Saharan African countries have introduced HPV vaccination programs at the national level in the last few years. However, countries are struggling to maintain sus...

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Autores principales: Waheed, Dur-E-Nayab, Bolio, Ana, Guillaume, Dominique, Sidibe, Anissa, Morgan, Christopher, Karafillakis, Emilie, Holloway, Megan, Van Damme, Pierre, Limaye, Rupali, Vorsters, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140426/
https://www.ncbi.nlm.nih.gov/pubmed/37124764
http://dx.doi.org/10.3389/fpubh.2023.1112981
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author Waheed, Dur-E-Nayab
Bolio, Ana
Guillaume, Dominique
Sidibe, Anissa
Morgan, Christopher
Karafillakis, Emilie
Holloway, Megan
Van Damme, Pierre
Limaye, Rupali
Vorsters, Alex
author_facet Waheed, Dur-E-Nayab
Bolio, Ana
Guillaume, Dominique
Sidibe, Anissa
Morgan, Christopher
Karafillakis, Emilie
Holloway, Megan
Van Damme, Pierre
Limaye, Rupali
Vorsters, Alex
author_sort Waheed, Dur-E-Nayab
collection PubMed
description Cervical cancer due to human papillomavirus (HPV) infection is a leading cause of mortality among women in low-resource settings. Many Sub-Saharan African countries have introduced HPV vaccination programs at the national level in the last few years. However, countries are struggling to maintain sustainable coverage. This study focuses on the introduction and sustainability challenges, context-specific key lessons learned, and mechanisms of action to achieve high sustainable coverage from low and lower-middle-income countries (LLMICs) that have introduced HPV vaccination programs by collating evidence from a literature review and key informant interviews. Local data availability was a challenge across countries, with the lack or absence of registries, data collection and reporting mechanisms. Multi-sectoral coordination and early involvement of key stakeholders were cited as an integral part of HPV programs and facilitators for sustainable coverage. Key informants identified periodic sensitization and training as critical due to high staff turnover. Health workforce mobilization was fundamental to ensure that the health workforce is aware of the disease etiology, eligibility requirements, and can dispel misinformation. Schools were reported to be an ideal sustainable platform for vaccination. However, this required teachers to be trained, which was often not considered in the programs. District-level staff were often poorly informed and lacked the technical and logistic capacity to support vaccination rounds and data collection. To improve the sustainability of HPV vaccination programs, there is a need for timely microplanning, efficient preparedness assessment, assessing training approaches, periodic training, finding innovative ways to achieve equity and adoption of a bottom-up approach to ensure that processes between districts and central level are well-connected and resources are distributed efficiently.
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spelling pubmed-101404262023-04-29 Planning, implementation, and sustaining high coverage of human papillomavirus (HPV) vaccination programs: What works in the context of low-resource countries? Waheed, Dur-E-Nayab Bolio, Ana Guillaume, Dominique Sidibe, Anissa Morgan, Christopher Karafillakis, Emilie Holloway, Megan Van Damme, Pierre Limaye, Rupali Vorsters, Alex Front Public Health Public Health Cervical cancer due to human papillomavirus (HPV) infection is a leading cause of mortality among women in low-resource settings. Many Sub-Saharan African countries have introduced HPV vaccination programs at the national level in the last few years. However, countries are struggling to maintain sustainable coverage. This study focuses on the introduction and sustainability challenges, context-specific key lessons learned, and mechanisms of action to achieve high sustainable coverage from low and lower-middle-income countries (LLMICs) that have introduced HPV vaccination programs by collating evidence from a literature review and key informant interviews. Local data availability was a challenge across countries, with the lack or absence of registries, data collection and reporting mechanisms. Multi-sectoral coordination and early involvement of key stakeholders were cited as an integral part of HPV programs and facilitators for sustainable coverage. Key informants identified periodic sensitization and training as critical due to high staff turnover. Health workforce mobilization was fundamental to ensure that the health workforce is aware of the disease etiology, eligibility requirements, and can dispel misinformation. Schools were reported to be an ideal sustainable platform for vaccination. However, this required teachers to be trained, which was often not considered in the programs. District-level staff were often poorly informed and lacked the technical and logistic capacity to support vaccination rounds and data collection. To improve the sustainability of HPV vaccination programs, there is a need for timely microplanning, efficient preparedness assessment, assessing training approaches, periodic training, finding innovative ways to achieve equity and adoption of a bottom-up approach to ensure that processes between districts and central level are well-connected and resources are distributed efficiently. Frontiers Media S.A. 2023-04-14 /pmc/articles/PMC10140426/ /pubmed/37124764 http://dx.doi.org/10.3389/fpubh.2023.1112981 Text en Copyright © 2023 Waheed, Bolio, Guillaume, Sidibe, Morgan, Karafillakis, Holloway, Van Damme, Limaye and Vorsters. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Waheed, Dur-E-Nayab
Bolio, Ana
Guillaume, Dominique
Sidibe, Anissa
Morgan, Christopher
Karafillakis, Emilie
Holloway, Megan
Van Damme, Pierre
Limaye, Rupali
Vorsters, Alex
Planning, implementation, and sustaining high coverage of human papillomavirus (HPV) vaccination programs: What works in the context of low-resource countries?
title Planning, implementation, and sustaining high coverage of human papillomavirus (HPV) vaccination programs: What works in the context of low-resource countries?
title_full Planning, implementation, and sustaining high coverage of human papillomavirus (HPV) vaccination programs: What works in the context of low-resource countries?
title_fullStr Planning, implementation, and sustaining high coverage of human papillomavirus (HPV) vaccination programs: What works in the context of low-resource countries?
title_full_unstemmed Planning, implementation, and sustaining high coverage of human papillomavirus (HPV) vaccination programs: What works in the context of low-resource countries?
title_short Planning, implementation, and sustaining high coverage of human papillomavirus (HPV) vaccination programs: What works in the context of low-resource countries?
title_sort planning, implementation, and sustaining high coverage of human papillomavirus (hpv) vaccination programs: what works in the context of low-resource countries?
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140426/
https://www.ncbi.nlm.nih.gov/pubmed/37124764
http://dx.doi.org/10.3389/fpubh.2023.1112981
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