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Treatment effects of soluble guanylate cyclase modulation on diabetic kidney disease at single-cell resolution

Diabetic kidney disease (DKD) is the most common cause of renal failure. Therapeutics development is hampered by our incomplete understanding of animal models on a cellular level. We show that ZSF1 rats recapitulate human DKD on a phenotypic and transcriptomic level. Tensor decomposition prioritizes...

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Detalles Bibliográficos
Autores principales:	Balzer, Michael S., Pavkovic, Mira, Frederick, Julia, Abedini, Amin, Freyberger, Alexius, Vienenkötter, Julia, Mathar, Ilka, Siudak, Krystyna, Eitner, Frank, Sandner, Peter, Grundmann, Manuel, Susztak, Katalin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140477/ https://www.ncbi.nlm.nih.gov/pubmed/37023747 http://dx.doi.org/10.1016/j.xcrm.2023.100992

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