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Determination of HIF-1α degradation pathways via modulation of the propionyl mark

The hypoxia-inducible factor-1α (HIF-1α) is a key regulator of hypoxic stress under physiological and pathological conditions. HIF-1α protein stability is tightly regulated by the ubiquitin-proteasome system (UPS) and autophagy in normoxia, hypoxia, and the tumor environment to mediate the hypoxic r...

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Detalles Bibliográficos
Autores principales:	Jeong, Kwanyoung, Choi, Jinmi, Choi, Ahrum, Shim, Joohee, Kim, Young Ah, Oh, Changseok, Youn, Hong-Duk, Cho, Eun-Jung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140483/ https://www.ncbi.nlm.nih.gov/pubmed/36789561 http://dx.doi.org/10.5483/BMBRep.2022-0191

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