Inhibition of macrophages inflammasome activation via autophagic degradation of HMGB1 by EGCG ameliorates HBV-induced liver injury and fibrosis

BACKGROUND: Liver fibrosis is a reversible wound-healing response that can lead to end-stage liver diseases without effective treatment, in which HBV infection is a major cause. However, the underlying mechanisms for the development of HBV-induced fibrosis remains elusive, and efficacious therapies...

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Detalles Bibliográficos
Autores principales: He, Minjing, Chu, Tianhao, Wang, Ziteng, Feng, Ying, Shi, Runhan, He, Muyang, Feng, Siheng, Lu, Lin, Cai, Chen, Fang, Fang, Zhang, Xuemin, Liu, Yi, Gao, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140519/
https://www.ncbi.nlm.nih.gov/pubmed/37122751
http://dx.doi.org/10.3389/fimmu.2023.1147379

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