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Development and evaluation of novel artemisinin-isatin hybrids with potential anti-leukemic cytotoxicity

Twenty-one novel ester tethered artemisinin-isatin hybrids were designed, synthesized and screened against human myeloid leukemia cell lines (K562 and K562/ADR), human acute lymphoblastic leukemia cell line (CCRF-CEM) as well as normal human peripheral blood mononuclear cells (PBMCs) for their cytot...

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Detalles Bibliográficos
Autores principales:	Wang, Peng, Zhang, Zhe, Cao, Wei, Zhang, Xuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140581/ https://www.ncbi.nlm.nih.gov/pubmed/37124527 http://dx.doi.org/10.3389/fonc.2023.1112369

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