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Synergistic effects of combined immunotherapy strategies in a model of multifocal hepatocellular carcinoma
Immune checkpoint-inhibitor combinations are the best therapeutic option for advanced hepatocellular carcinoma (HCC) patients, but improvements in efficacy are needed to improve response rates. We develop a multifocal HCC model to test immunotherapies by introducing c-myc using hydrodynamic gene tra...
Autores principales: | Ochoa, Maria Carmen, Sanchez-Gregorio, Sandra, de Andrea, Carlos E., Garasa, Saray, Alvarez, Maite, Olivera, Irene, Glez-Vaz, Javier, Luri-Rey, Carlos, Etxeberria, Iñaki, Cirella, Assunta, Azpilikueta, Arantza, Berraondo, Pedro, Argemi, Josepmaria, Sangro, Bruno, Teijeira, Alvaro, Melero, Ignacio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140615/ https://www.ncbi.nlm.nih.gov/pubmed/37040772 http://dx.doi.org/10.1016/j.xcrm.2023.101009 |
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