Cargando…

Organocatalysed one-pot three component synthesis of 3,3′-disubstituted oxindoles featuring an all-carbon quaternary center and spiro[2H-pyran-3,4′-indoline]

A simple and efficient methodology for the one-pot synthesis of 3,3′-disubstituted oxindoles featuring an all-carbon quaternary center has been demonstrated through l-proline catalysed three-component reaction based on sequential Knoevenagel condensation/Michael addition and also one-pot synthesis o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nichinde, Chandrakant B., Patil, Baliram R., Chaudhari, Suryakant S., Mali, Bhupendra P., Gonnade, Rajesh G., Kinage, Anil K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140734/ https://www.ncbi.nlm.nih.gov/pubmed/37123998 http://dx.doi.org/10.1039/d3ra00510k

Ejemplares similares

Spiro[pyrrolidine-3,3′-oxindoles] and Their Indoline Analogues as New 5-HT6 Receptor Chemotypes
por: Kelemen, Ádám A., et al.
Publicado: (2017)

Tri(n-butyl)phosphine-promoted domino reaction for the efficient construction of spiro[cyclohexane-1,3'-indolines] and spiro[indoline-3,2'-furan-3',3''-indolines]
por: Zheng, Hui, et al.
Publicado: (2022)

Oxidative organocatalysed enantioselective coupling of indoles with aldehydes that forms quaternary carbon stereocentres
por: Rezayee, Nomaan M., et al.
Publicado: (2019)

5′-Amino-2-oxo-2′,3′-dihydrospiro[indoline-3,7′-thieno[3,2-b]pyran]-6′-carbonitrile 1′,1′-dioxide
por: Shen, Shi-De, et al.
Publicado: (2010)

Synthesis of functionalized spiro[indoline-3,4’-pyridines] and spiro[indoline-3,4’-pyridinones] via one-pot four-component reactions
por: Zhang, Li-Juan, et al.
Publicado: (2013)

Spiro[1,3-dioxolane-2,3′-indolin]-2′-one
por: Meng, Yan, et al.
Publicado: (2010)

Ammonium chloride catalyzed synthesis of novel Schiff bases from spiro[indoline-3,4′-pyran]-3′-carbonitriles and evaluation of their antimicrobial and anti-breast cancer activities
por: Al-Shareef, Hossa F., et al.
Publicado: (2016)

Spiro[cyclopropane-1,3′-indolin]-2′-one
por: Yuan, Maosen, et al.
Publicado: (2011)

Ascorbic Acid-Initiated Tandem Radical Cyclization of N-Arylacrylamides to Give 3,3-Disubstituted Oxindoles
por: Liu, Sheng, et al.
Publicado: (2015)

Literature Survey and Further Studies on the 3-Alkylation of N-Unprotected 3-Monosubstituted Oxindoles. Practical Synthesis of N-Unprotected 3,3-Disubstituted Oxindoles and Subsequent Transformations on the Aromatic Ring
por: Kókai, Eszter, et al.
Publicado: (2016)

Ring-opening cyclization of activated spiro-aziridine oxindoles with heteroarenes: a facile synthetic approach to spiro-oxindole-fused pyrroloindolines
por: Bhandari, Sonal, et al.
Publicado: (2020)

1-Benzyl-4′,5′-diphenylpiperidine-3-spiro-3′-pyrrolidine-2′-spiro-3′′-indoline-4,2′′-dione
por: Suresh, J., et al.
Publicado: (2008)

1′-Methyl-2,2′′-dioxoindoline-3-spiro-2′-pyrrolidine-3′-spiro-3′′-indoline-4′,4′-dicarbonitrile
por: Ramesh, P., et al.
Publicado: (2009)

Access to 3,3-disubstituted oxindoles via microwave-assisted Cannizzaro and aldol reactions of formaldehyde with isatins and their imines
por: Huang, Xuan, et al.
Publicado: (2021)

Crystal structure and Hirshfeld surface analysis of ethyl 2′-amino-5-bromo-3′-cyano-6′-methyl-2-oxospiro[indoline-3,4′-pyran]-5′-carboxylate
por: Naghiyev, Farid N., et al.
Publicado: (2022)

A Facile One-Pot Construction of Succinimide-Fused Spiro[Pyrrolidine-2,3′-Oxindoles] via 1,3-Dipolar Cycloaddition Involving 3-Amino Oxindoles and Maleimides
por: Jin, Lunqiang, et al.
Publicado: (2018)

5-Chlorobenzothiazole-2-spiro-3′-indolin-2′-one
por: Akkurt, Mehmet, et al.
Publicado: (2010)

Highly Diastereo- and Enantioselective CuH-Catalyzed Synthesis of 2,3-Disubstituted Indolines
por: Ascic, Erhad, et al.
Publicado: (2015)

Gold-catalyzed stereoselective dearomatization/metal-free aerobic oxidation: access to 3-substituted indolines/oxindoles
por: Liu, Kai, et al.
Publicado: (2017)

Studies on the Enantioselective Synthesis of E-Ethylidene-bearing Spiro[indolizidine-1,3′-oxindole] Alkaloids
por: Yayik, Nihan, et al.
Publicado: (2021)

Sonochemistry in an organocatalytic domino reaction: an expedient multicomponent access to structurally functionalized dihydropyrano[3,2-b]pyrans, spiro-pyrano[3,2-b]pyrans, and spiro-indenoquinoxaline-pyranopyrans under ambient conditions
por: Borah, Biplob, et al.
Publicado: (2022)

Methyl 5′′-chloro-1′,1′′-dimethyl-2,2′′-dioxodispiro[indoline-3,2′-pyrrolidine-3′,3′′-indoline]-4′-carboxylate
por: Kannan, Piskala Subburaman, et al.
Publicado: (2013)

1′-Phenyl-6′-thiacycloheptane-1-spiro-2′-perhydropyrrolizine-3′-spiro-3′′-indoline-2,2′′-dione
por: Sundaramoorthy, S., et al.
Publicado: (2008)

Crystal structure determination as part of an undergraduate laboratory experiment: 1′,3′,3′-trimethylspiro[chromene-2,2′-indoline] and 1′,3′,3′-trimethyl-4-[(E)-(1,3,3-trimethylindolin-2-ylidene)methyl]spiro[chroman-2,2′-indoline]
por: Beckett, Joseph O. S., et al.
Publicado: (2016)

Synthesis of spiro[indoline-3,1[Formula: see text] -quinolizines] and spiro[indoline-3,4[Formula: see text] -pyrido[1,2-a]quinolines] via three-component reactions of azaarenes, acetylenedicarboxylate, and 3-methyleneoxindoles
por: Sun, Jing, et al.
Publicado: (2013)

5,6-Dimethoxy-4′,5′-diphenylindane-2-spiro-3′-pyrrolidine-2′-spiro-3′′-indoline-1,2′′-dione
por: Ali, Mohamed Ashraf, et al.
Publicado: (2010)

Ethyl 6′-amino-5′-cyano-2′-methyl-2-oxospiro[indoline-3,4′-pyran]-3′-carboxylate
por: Wang, Jing, et al.
Publicado: (2009)

Methyl 6′-amino-5′-cyano-2′-methyl-2-oxospiro[indoline-3,4′-pyran]-3′-carboxylate
por: Zhu, Song-Lei, et al.
Publicado: (2010)

4′-(2,4-Dichlorophenyl)-1,1′-dimethylpiperidine-3-spiro-3′-pyrrolidine-2′-spiro-3′′-indoline-4,2′′-dione
por: Nagamuthu, S., et al.
Publicado: (2010)

Crystal structure and Hirshfeld surface analysis of ethyl 6′-amino-2′-(chloromethyl)-5′-cyano-2-oxo-1,2-dihydrospiro[indoline-3,4′-pyran]-3′-carboxylate
por: Naghiyev, Farid N., et al.
Publicado: (2021)

Facile synthesis of functionalized spiro[indoline-3,2'-oxiran]-2-ones by Darzens reaction
por: Fu, Qin, et al.
Publicado: (2013)

An Efficient Synthesis of Spiro[indoline-3,9′-xanthene]trione Derivatives Catalyzed by Magnesium Perchlorate
por: Chen, Chunfeng, et al.
Publicado: (2017)

Synthesis of spiro[dihydropyridine-oxindoles] via three-component reaction of arylamine, isatin and cyclopentane-1,3-dione
por: Sun, Yan, et al.
Publicado: (2013)

The Solubility Studies and the Complexation Mechanism Investigations of Biologically Active Spiro[cyclopropane-1,3′-oxindoles] with β-Cyclodextrins
por: Kravtsova, Anna A., et al.
Publicado: (2023)

1′′-Benzyl-1′-methyl-4′-(naphthalen-1-yl)naphthalene-2-spiro-3′-pyrrolidine-2′-spiro-3′′-indoline-1,2′′-dione
por: Selvanayagam, S., et al.
Publicado: (2011)

(1′S)-4-(3,4-Dichlorophenyl)-1′-(3,5-dimethoxyphenyl)-1,2,3,4-tetrahydronaphthalene-2-spiro-2′-pyrrolizidine-3′-spiro-3′′-indoline-1,2′′-dione
por: Kamala, E. Theboral Sugi, et al.
Publicado: (2008)

Spiro[pyrrolidine-3, 3´-oxindole] as potent anti-breast cancer compounds: Their design, synthesis, biological evaluation and cellular target identification
por: Hati, Santanu, et al.
Publicado: (2016)

1′-Methyl-2-oxo-5′-phenylspiro[indoline-3,3′-pyrrolidine]-4′,4′-dicarbonitrile
por: Nabid, Mohammad Reza, et al.
Publicado: (2009)

5′,6-Dichloro-1′,3′,3′-trimethylspiro[2H-1-benzopyran-2,2′-indoline]
por: Alhashimy, Nameer, et al.
Publicado: (2008)

5′-Chlorospiro[1,3-dioxolane-2,3′-indolin]-2′-one: a potential anticonvulsant
por: De, Amitabha
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_p3ccu4hnj0lbtgemhmjj9enqeu