Disruption to tRNA Modification by Queuine Contributes to Inflammatory Bowel Disease

BACKGROUNDS AND AIMS: Transfer RNA (tRNA) is the most extensively modified RNA in cells. Queuosine modification is a fundamental process for ensuring the fidelity and efficiency of translation from RNA to protein. In eukaryotes, Queuosine tRNA (Q-tRNA) modification relies on the intestinal microbial...

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Detalles Bibliográficos
Autores principales: Zhang, Jilei, Zhang, Yongguo, McGrenaghan, Callum J., Kelly, Vincent P., Xia, Yinglin, Sun, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140797/
https://www.ncbi.nlm.nih.gov/pubmed/36801450
http://dx.doi.org/10.1016/j.jcmgh.2023.02.006

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