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PFKFB4 Drives the Oncogenicity in TP53-Mutated Hepatocellular Carcinoma in a Phosphatase-Dependent Manner

BACKGROUND & AIMS: Metabolic reprogramming is recognized as a cancer hallmark intimately linked to tumor hypoxia, which supports rapid tumor growth and mitigates the consequential oxidative stress. Phosphofructokinase-fructose bisphosphatase (PFKFB) is a family of bidirectional glycolytic enzyme...

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Detalles Bibliográficos
Autores principales:	Kam, Charles Shing, Ho, Daniel Wai-Hung, Ming, Vanessa Sheung-In, Tian, Lu, Sze, Karen Man-Fong, Zhang, Vanilla Xin, Tsui, Yu-Man, Husain, Abdullah, Lee, Joyce Man-Fong, Wong, Carmen Chak-Lui, Chan, Albert Chi-Yan, Cheung, Tan-To, Chan, Lo-Kong, Ng, Irene Oi-Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140800/ https://www.ncbi.nlm.nih.gov/pubmed/36806581 http://dx.doi.org/10.1016/j.jcmgh.2023.02.004

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