Predicting Hydroxychloroquine Clearance in Healthy and Diseased Populations Using a Physiologically Based Pharmacokinetic Approach

Hydroxychloroquine (HCQ), a congener of chloroquine, is widely used in prophylaxis and the treatment of malaria, and also as a cure for rheumatoid arthritis, systemic lupus erythematosus, and various other diseases. Physiologically based pharmacokinetic modeling (PBPK) has attracted great interest i...

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Detalles Bibliográficos
Autores principales: Alqahtani, Faleh, Asiri, Ali Mohammed, Zamir, Ammara, Rasool, Muhammad Fawad, Alali, Amer S., Alsanea, Sary, Walbi, Ismail A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140819/
https://www.ncbi.nlm.nih.gov/pubmed/37111735
http://dx.doi.org/10.3390/pharmaceutics15041250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140819/
https://www.ncbi.nlm.nih.gov/pubmed/37111735
http://dx.doi.org/10.3390/pharmaceutics15041250

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