Double Mutations in a Patient with Early-Onset Alzheimer’s Disease in Korea: An APP Val551Met and a PSEN2 His169Asn

The etiology of early-onset Alzheimer’s disease (EOAD) is associated with alterations in the production of amyloid beta (Aβ) species caused by mutations in the APP, PSEN1, and PSEN2 genes. Mutations affect intra- or inter-molecular interactions and processes between the γ-secretase complex and amylo...

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Detalles Bibliográficos
Autores principales: Bae, Heewon, Shim, Kyu Hwan, Yoo, Jang, Yang, Young-Soon, An, Seong Soo A., Kang, Min-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140908/
https://www.ncbi.nlm.nih.gov/pubmed/37108607
http://dx.doi.org/10.3390/ijms24087446

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140908/
https://www.ncbi.nlm.nih.gov/pubmed/37108607
http://dx.doi.org/10.3390/ijms24087446

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