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A Novel Risk Calculator to Predict Erectile Dysfunction in HIV-Positive Men
HIV infection is considered to be a lifelong medical condition, requiring follow-up and treatment for decades. HIV-positive men are reported to have erectile dysfunction more often than age-matched healthy controls, and improving sexuality is known to potentially improve overall health-related quali...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140986/ https://www.ncbi.nlm.nih.gov/pubmed/37109065 http://dx.doi.org/10.3390/jpm13040679 |
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author | Chirca, Narcis Streinu-Cercel, Anca Stefan, Marius Aurelian, Justin Persu, Cristian |
author_facet | Chirca, Narcis Streinu-Cercel, Anca Stefan, Marius Aurelian, Justin Persu, Cristian |
author_sort | Chirca, Narcis |
collection | PubMed |
description | HIV infection is considered to be a lifelong medical condition, requiring follow-up and treatment for decades. HIV-positive men are reported to have erectile dysfunction more often than age-matched healthy controls, and improving sexuality is known to potentially improve overall health-related quality of life. The aim of this paper is to evaluate the presence of ED in HIV-positive men and the associated contributing factors and to create a statistical model to assess the risk to develop ED in this population. In a prospective study, we analyzed a group of HIV-positive men in a cross-sectional manner, looking at demographics, blood test results, and smoking habits. Data were statistically analyzed using the Kruskal–Wallis test. In our series, the overall incidence of ED was 48.5%, increasing with age. Our analysis showed no correlation with blood sugar level, but a very strong correlation with total serum lipids. We were able to develop and validate a risk calculator for ED in HIV-positive men. |
format | Online Article Text |
id | pubmed-10140986 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-101409862023-04-29 A Novel Risk Calculator to Predict Erectile Dysfunction in HIV-Positive Men Chirca, Narcis Streinu-Cercel, Anca Stefan, Marius Aurelian, Justin Persu, Cristian J Pers Med Article HIV infection is considered to be a lifelong medical condition, requiring follow-up and treatment for decades. HIV-positive men are reported to have erectile dysfunction more often than age-matched healthy controls, and improving sexuality is known to potentially improve overall health-related quality of life. The aim of this paper is to evaluate the presence of ED in HIV-positive men and the associated contributing factors and to create a statistical model to assess the risk to develop ED in this population. In a prospective study, we analyzed a group of HIV-positive men in a cross-sectional manner, looking at demographics, blood test results, and smoking habits. Data were statistically analyzed using the Kruskal–Wallis test. In our series, the overall incidence of ED was 48.5%, increasing with age. Our analysis showed no correlation with blood sugar level, but a very strong correlation with total serum lipids. We were able to develop and validate a risk calculator for ED in HIV-positive men. MDPI 2023-04-18 /pmc/articles/PMC10140986/ /pubmed/37109065 http://dx.doi.org/10.3390/jpm13040679 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Chirca, Narcis Streinu-Cercel, Anca Stefan, Marius Aurelian, Justin Persu, Cristian A Novel Risk Calculator to Predict Erectile Dysfunction in HIV-Positive Men |
title | A Novel Risk Calculator to Predict Erectile Dysfunction in HIV-Positive Men |
title_full | A Novel Risk Calculator to Predict Erectile Dysfunction in HIV-Positive Men |
title_fullStr | A Novel Risk Calculator to Predict Erectile Dysfunction in HIV-Positive Men |
title_full_unstemmed | A Novel Risk Calculator to Predict Erectile Dysfunction in HIV-Positive Men |
title_short | A Novel Risk Calculator to Predict Erectile Dysfunction in HIV-Positive Men |
title_sort | novel risk calculator to predict erectile dysfunction in hiv-positive men |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140986/ https://www.ncbi.nlm.nih.gov/pubmed/37109065 http://dx.doi.org/10.3390/jpm13040679 |
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