Cargando…

A Novel Risk Calculator to Predict Erectile Dysfunction in HIV-Positive Men

HIV infection is considered to be a lifelong medical condition, requiring follow-up and treatment for decades. HIV-positive men are reported to have erectile dysfunction more often than age-matched healthy controls, and improving sexuality is known to potentially improve overall health-related quali...

Descripción completa

Detalles Bibliográficos
Autores principales: Chirca, Narcis, Streinu-Cercel, Anca, Stefan, Marius, Aurelian, Justin, Persu, Cristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140986/
https://www.ncbi.nlm.nih.gov/pubmed/37109065
http://dx.doi.org/10.3390/jpm13040679
_version_ 1785033284238966784
author Chirca, Narcis
Streinu-Cercel, Anca
Stefan, Marius
Aurelian, Justin
Persu, Cristian
author_facet Chirca, Narcis
Streinu-Cercel, Anca
Stefan, Marius
Aurelian, Justin
Persu, Cristian
author_sort Chirca, Narcis
collection PubMed
description HIV infection is considered to be a lifelong medical condition, requiring follow-up and treatment for decades. HIV-positive men are reported to have erectile dysfunction more often than age-matched healthy controls, and improving sexuality is known to potentially improve overall health-related quality of life. The aim of this paper is to evaluate the presence of ED in HIV-positive men and the associated contributing factors and to create a statistical model to assess the risk to develop ED in this population. In a prospective study, we analyzed a group of HIV-positive men in a cross-sectional manner, looking at demographics, blood test results, and smoking habits. Data were statistically analyzed using the Kruskal–Wallis test. In our series, the overall incidence of ED was 48.5%, increasing with age. Our analysis showed no correlation with blood sugar level, but a very strong correlation with total serum lipids. We were able to develop and validate a risk calculator for ED in HIV-positive men.
format Online
Article
Text
id pubmed-10140986
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-101409862023-04-29 A Novel Risk Calculator to Predict Erectile Dysfunction in HIV-Positive Men Chirca, Narcis Streinu-Cercel, Anca Stefan, Marius Aurelian, Justin Persu, Cristian J Pers Med Article HIV infection is considered to be a lifelong medical condition, requiring follow-up and treatment for decades. HIV-positive men are reported to have erectile dysfunction more often than age-matched healthy controls, and improving sexuality is known to potentially improve overall health-related quality of life. The aim of this paper is to evaluate the presence of ED in HIV-positive men and the associated contributing factors and to create a statistical model to assess the risk to develop ED in this population. In a prospective study, we analyzed a group of HIV-positive men in a cross-sectional manner, looking at demographics, blood test results, and smoking habits. Data were statistically analyzed using the Kruskal–Wallis test. In our series, the overall incidence of ED was 48.5%, increasing with age. Our analysis showed no correlation with blood sugar level, but a very strong correlation with total serum lipids. We were able to develop and validate a risk calculator for ED in HIV-positive men. MDPI 2023-04-18 /pmc/articles/PMC10140986/ /pubmed/37109065 http://dx.doi.org/10.3390/jpm13040679 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Chirca, Narcis
Streinu-Cercel, Anca
Stefan, Marius
Aurelian, Justin
Persu, Cristian
A Novel Risk Calculator to Predict Erectile Dysfunction in HIV-Positive Men
title A Novel Risk Calculator to Predict Erectile Dysfunction in HIV-Positive Men
title_full A Novel Risk Calculator to Predict Erectile Dysfunction in HIV-Positive Men
title_fullStr A Novel Risk Calculator to Predict Erectile Dysfunction in HIV-Positive Men
title_full_unstemmed A Novel Risk Calculator to Predict Erectile Dysfunction in HIV-Positive Men
title_short A Novel Risk Calculator to Predict Erectile Dysfunction in HIV-Positive Men
title_sort novel risk calculator to predict erectile dysfunction in hiv-positive men
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140986/
https://www.ncbi.nlm.nih.gov/pubmed/37109065
http://dx.doi.org/10.3390/jpm13040679
work_keys_str_mv AT chircanarcis anovelriskcalculatortopredicterectiledysfunctioninhivpositivemen
AT streinucercelanca anovelriskcalculatortopredicterectiledysfunctioninhivpositivemen
AT stefanmarius anovelriskcalculatortopredicterectiledysfunctioninhivpositivemen
AT aurelianjustin anovelriskcalculatortopredicterectiledysfunctioninhivpositivemen
AT persucristian anovelriskcalculatortopredicterectiledysfunctioninhivpositivemen
AT chircanarcis novelriskcalculatortopredicterectiledysfunctioninhivpositivemen
AT streinucercelanca novelriskcalculatortopredicterectiledysfunctioninhivpositivemen
AT stefanmarius novelriskcalculatortopredicterectiledysfunctioninhivpositivemen
AT aurelianjustin novelriskcalculatortopredicterectiledysfunctioninhivpositivemen
AT persucristian novelriskcalculatortopredicterectiledysfunctioninhivpositivemen