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Heterogeneity in Vaccinal Immunity to SARS-CoV-2 Can Be Addressed by a Personalized Booster Strategy
SARS-CoV-2 vaccinations were initially shown to substantially reduce risk of severe disease and death. However, pharmacokinetic (PK) waning and rapid viral evolution degrade neutralizing antibody (nAb) binding titers, causing loss of vaccinal protection. Additionally, there is inter-individual heter...
Autores principales: | Stoddard, Madison, Yuan, Lin, Sarkar, Sharanya, Mangalaganesh, Shruthi, Nolan, Ryan P., Bottino, Dean, Hather, Greg, Hochberg, Natasha S., White, Laura F., Chakravarty, Arijit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10140995/ https://www.ncbi.nlm.nih.gov/pubmed/37112718 http://dx.doi.org/10.3390/vaccines11040806 |
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