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Biochemical Profile and In Vitro Therapeutic Properties of Two Euhalophytes, Halocnemum strobilaceum Pall. and Suaeda fruticosa (L.) Forske., Grown in the Sabkha Ecosystem in the Algerian Sahara

This study reports the biochemical profile and in vitro biological activities of the aerial part of two shrubs: Halocnemum strobilaceum and Suaeda fruticosa, a halophytes species native to saline habitats. The biomass was evaluated by determining its physiological properties and approximate composit...

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Autores principales: Gheraissa, Noura, Chemsa, Ahmed Elkhalifa, Cherrada, Nezar, Erol, Ebru, Elsharkawy, Eman Ramadan, Ghemam-Amara, Djilani, Zeghoud, Soumeia, Rebiai, Abdelkrim, Messaoudi, Mohammed, Sawicka, Barbara, Atanassova, Maria, Abdel-Kader, Maged S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141351/
https://www.ncbi.nlm.nih.gov/pubmed/37110814
http://dx.doi.org/10.3390/molecules28083580
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author Gheraissa, Noura
Chemsa, Ahmed Elkhalifa
Cherrada, Nezar
Erol, Ebru
Elsharkawy, Eman Ramadan
Ghemam-Amara, Djilani
Zeghoud, Soumeia
Rebiai, Abdelkrim
Messaoudi, Mohammed
Sawicka, Barbara
Atanassova, Maria
Abdel-Kader, Maged S.
author_facet Gheraissa, Noura
Chemsa, Ahmed Elkhalifa
Cherrada, Nezar
Erol, Ebru
Elsharkawy, Eman Ramadan
Ghemam-Amara, Djilani
Zeghoud, Soumeia
Rebiai, Abdelkrim
Messaoudi, Mohammed
Sawicka, Barbara
Atanassova, Maria
Abdel-Kader, Maged S.
author_sort Gheraissa, Noura
collection PubMed
description This study reports the biochemical profile and in vitro biological activities of the aerial part of two shrubs: Halocnemum strobilaceum and Suaeda fruticosa, a halophytes species native to saline habitats. The biomass was evaluated by determining its physiological properties and approximate composition. Hydro-methanolic extracts from Halocnemum strobilaceum and Suaeda fruticosa have been investigated for the inhibition of bacterial growth, the protection of proteins (albumin) from denaturation, and cytotoxicity to hepatocellular carcinomas (Huh-7 and HepG2). Their antioxidant activity was evaluated by five tests, including one that examined their ability to inhibit hydrogen peroxide (H(2)O(2))-induced hemolysis. The profile of their phenolic compounds was also determined. These two euhalophytes had a high moisture content, high levels of photosynthetic pigments, elevated levels of ash and protein, low oxidative damage indices, MDA (Malondialdehyde) and proline, and low lipids levels. Their content was also characterized by a moderate acidity with good electrical conductivity. They contained abundant levels of phytochemicals and varied phenolic contents. Reverse phase high performance liquid chromatography (RP-HPLC) analysis revealed the presence of caffeic acid, p-coumaric acid, rutin, and quercetin in both plant extracts. On the pharmaceutical level, the two euhalophytes had anti-inflammatory, antibacterial, antioxidant, and cytotoxic properties, and therefore it was recommended to isolate and identify biologically active compounds from these plants and evaluate them in vivo.
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spelling pubmed-101413512023-04-29 Biochemical Profile and In Vitro Therapeutic Properties of Two Euhalophytes, Halocnemum strobilaceum Pall. and Suaeda fruticosa (L.) Forske., Grown in the Sabkha Ecosystem in the Algerian Sahara Gheraissa, Noura Chemsa, Ahmed Elkhalifa Cherrada, Nezar Erol, Ebru Elsharkawy, Eman Ramadan Ghemam-Amara, Djilani Zeghoud, Soumeia Rebiai, Abdelkrim Messaoudi, Mohammed Sawicka, Barbara Atanassova, Maria Abdel-Kader, Maged S. Molecules Article This study reports the biochemical profile and in vitro biological activities of the aerial part of two shrubs: Halocnemum strobilaceum and Suaeda fruticosa, a halophytes species native to saline habitats. The biomass was evaluated by determining its physiological properties and approximate composition. Hydro-methanolic extracts from Halocnemum strobilaceum and Suaeda fruticosa have been investigated for the inhibition of bacterial growth, the protection of proteins (albumin) from denaturation, and cytotoxicity to hepatocellular carcinomas (Huh-7 and HepG2). Their antioxidant activity was evaluated by five tests, including one that examined their ability to inhibit hydrogen peroxide (H(2)O(2))-induced hemolysis. The profile of their phenolic compounds was also determined. These two euhalophytes had a high moisture content, high levels of photosynthetic pigments, elevated levels of ash and protein, low oxidative damage indices, MDA (Malondialdehyde) and proline, and low lipids levels. Their content was also characterized by a moderate acidity with good electrical conductivity. They contained abundant levels of phytochemicals and varied phenolic contents. Reverse phase high performance liquid chromatography (RP-HPLC) analysis revealed the presence of caffeic acid, p-coumaric acid, rutin, and quercetin in both plant extracts. On the pharmaceutical level, the two euhalophytes had anti-inflammatory, antibacterial, antioxidant, and cytotoxic properties, and therefore it was recommended to isolate and identify biologically active compounds from these plants and evaluate them in vivo. MDPI 2023-04-19 /pmc/articles/PMC10141351/ /pubmed/37110814 http://dx.doi.org/10.3390/molecules28083580 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gheraissa, Noura
Chemsa, Ahmed Elkhalifa
Cherrada, Nezar
Erol, Ebru
Elsharkawy, Eman Ramadan
Ghemam-Amara, Djilani
Zeghoud, Soumeia
Rebiai, Abdelkrim
Messaoudi, Mohammed
Sawicka, Barbara
Atanassova, Maria
Abdel-Kader, Maged S.
Biochemical Profile and In Vitro Therapeutic Properties of Two Euhalophytes, Halocnemum strobilaceum Pall. and Suaeda fruticosa (L.) Forske., Grown in the Sabkha Ecosystem in the Algerian Sahara
title Biochemical Profile and In Vitro Therapeutic Properties of Two Euhalophytes, Halocnemum strobilaceum Pall. and Suaeda fruticosa (L.) Forske., Grown in the Sabkha Ecosystem in the Algerian Sahara
title_full Biochemical Profile and In Vitro Therapeutic Properties of Two Euhalophytes, Halocnemum strobilaceum Pall. and Suaeda fruticosa (L.) Forske., Grown in the Sabkha Ecosystem in the Algerian Sahara
title_fullStr Biochemical Profile and In Vitro Therapeutic Properties of Two Euhalophytes, Halocnemum strobilaceum Pall. and Suaeda fruticosa (L.) Forske., Grown in the Sabkha Ecosystem in the Algerian Sahara
title_full_unstemmed Biochemical Profile and In Vitro Therapeutic Properties of Two Euhalophytes, Halocnemum strobilaceum Pall. and Suaeda fruticosa (L.) Forske., Grown in the Sabkha Ecosystem in the Algerian Sahara
title_short Biochemical Profile and In Vitro Therapeutic Properties of Two Euhalophytes, Halocnemum strobilaceum Pall. and Suaeda fruticosa (L.) Forske., Grown in the Sabkha Ecosystem in the Algerian Sahara
title_sort biochemical profile and in vitro therapeutic properties of two euhalophytes, halocnemum strobilaceum pall. and suaeda fruticosa (l.) forske., grown in the sabkha ecosystem in the algerian sahara
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141351/
https://www.ncbi.nlm.nih.gov/pubmed/37110814
http://dx.doi.org/10.3390/molecules28083580
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