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Quality of Life in Cervical Cancer Survivors Treated with Concurrent Chemoradiotherapy

Background and Objectives: Cervical cancer is the fourth most common cancer in women globally. As survival rates gradually increase, it becomes necessary to assess the quality of life (QoL) after treatment. It is known that different treatment modalities have different effects on QoL. Therefore, we...

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Autores principales: Stuopelytė, Raminta, Žukienė, Guoda, Breivienė, Rūta, Rudaitis, Vilius, Bartkevičienė, Daiva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141383/
https://www.ncbi.nlm.nih.gov/pubmed/37109735
http://dx.doi.org/10.3390/medicina59040777
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author Stuopelytė, Raminta
Žukienė, Guoda
Breivienė, Rūta
Rudaitis, Vilius
Bartkevičienė, Daiva
author_facet Stuopelytė, Raminta
Žukienė, Guoda
Breivienė, Rūta
Rudaitis, Vilius
Bartkevičienė, Daiva
author_sort Stuopelytė, Raminta
collection PubMed
description Background and Objectives: Cervical cancer is the fourth most common cancer in women globally. As survival rates gradually increase, it becomes necessary to assess the quality of life (QoL) after treatment. It is known that different treatment modalities have different effects on QoL. Therefore, we aimed to evaluate the QoL of cervical cancer survivors (CCSs) treated with concurrent chemoradiotherapy (CCRT). Materials and Methods: A cross-sectional monocentric study, conducted in Vilnius university hospital Santaros klinikos between November 2018 and November 2022, included 20 women, who were interviewed once using the European Organization for Research and Treatment of Cancer (EORTC)-designed Quality-of-Life questionnaire cervical cancer module (QLQ-CX24). The sociodemographic and clinical data as well as the results of the questionnaire are presented in mean, standard deviation and percentages. The QoL scores were compared between different age and stage groups using the Mann–Whitney U test. Results: Twenty participants, aged from 27 to 55 years, with a mean age of 44 years (SD = 7.6) participated in the study. All the participants were CCSs with an International Federation of Gynecology and Obstetrics (FIGO) stage from IB to IIIB and all of them were treated with CCRT. The symptom experience was relatively low and revealed a good result (21.8, SD = 10.2). Mean scores on body image, sexual/vaginal functioning, menopausal symptoms and sexual worry scales indicated moderate functioning and a moderate level of some of the cervical cancer specific symptoms after CCRT. Sexual activity and sexual enjoyment of the CCSs were low (11.7 (SD = 16.3), 14.3 (SD = 17.8), respectively). Conclusions: Cervical cancer survivors report a relatively good quality of life regarding symptom experience; however, women following concurrent chemoradiotherapy tend not to be sexually active and rarely feel sexual enjoyment. In addition, this treatment modality negatively affects a woman’s body image and self-perception as a woman.
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spelling pubmed-101413832023-04-29 Quality of Life in Cervical Cancer Survivors Treated with Concurrent Chemoradiotherapy Stuopelytė, Raminta Žukienė, Guoda Breivienė, Rūta Rudaitis, Vilius Bartkevičienė, Daiva Medicina (Kaunas) Article Background and Objectives: Cervical cancer is the fourth most common cancer in women globally. As survival rates gradually increase, it becomes necessary to assess the quality of life (QoL) after treatment. It is known that different treatment modalities have different effects on QoL. Therefore, we aimed to evaluate the QoL of cervical cancer survivors (CCSs) treated with concurrent chemoradiotherapy (CCRT). Materials and Methods: A cross-sectional monocentric study, conducted in Vilnius university hospital Santaros klinikos between November 2018 and November 2022, included 20 women, who were interviewed once using the European Organization for Research and Treatment of Cancer (EORTC)-designed Quality-of-Life questionnaire cervical cancer module (QLQ-CX24). The sociodemographic and clinical data as well as the results of the questionnaire are presented in mean, standard deviation and percentages. The QoL scores were compared between different age and stage groups using the Mann–Whitney U test. Results: Twenty participants, aged from 27 to 55 years, with a mean age of 44 years (SD = 7.6) participated in the study. All the participants were CCSs with an International Federation of Gynecology and Obstetrics (FIGO) stage from IB to IIIB and all of them were treated with CCRT. The symptom experience was relatively low and revealed a good result (21.8, SD = 10.2). Mean scores on body image, sexual/vaginal functioning, menopausal symptoms and sexual worry scales indicated moderate functioning and a moderate level of some of the cervical cancer specific symptoms after CCRT. Sexual activity and sexual enjoyment of the CCSs were low (11.7 (SD = 16.3), 14.3 (SD = 17.8), respectively). Conclusions: Cervical cancer survivors report a relatively good quality of life regarding symptom experience; however, women following concurrent chemoradiotherapy tend not to be sexually active and rarely feel sexual enjoyment. In addition, this treatment modality negatively affects a woman’s body image and self-perception as a woman. MDPI 2023-04-17 /pmc/articles/PMC10141383/ /pubmed/37109735 http://dx.doi.org/10.3390/medicina59040777 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Stuopelytė, Raminta
Žukienė, Guoda
Breivienė, Rūta
Rudaitis, Vilius
Bartkevičienė, Daiva
Quality of Life in Cervical Cancer Survivors Treated with Concurrent Chemoradiotherapy
title Quality of Life in Cervical Cancer Survivors Treated with Concurrent Chemoradiotherapy
title_full Quality of Life in Cervical Cancer Survivors Treated with Concurrent Chemoradiotherapy
title_fullStr Quality of Life in Cervical Cancer Survivors Treated with Concurrent Chemoradiotherapy
title_full_unstemmed Quality of Life in Cervical Cancer Survivors Treated with Concurrent Chemoradiotherapy
title_short Quality of Life in Cervical Cancer Survivors Treated with Concurrent Chemoradiotherapy
title_sort quality of life in cervical cancer survivors treated with concurrent chemoradiotherapy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141383/
https://www.ncbi.nlm.nih.gov/pubmed/37109735
http://dx.doi.org/10.3390/medicina59040777
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