Profiling Germinal Center-like B Cell Responses to Conjugate Vaccines Using Synthetic Immune Organoids

[Image: see text] Glycoengineered bacteria have emerged as a cost-effective platform for rapid and controllable biosynthesis of designer conjugate vaccines. However, little is known about the engagement of such conjugates with naïve B cells to induce the formation of germinal centers (GC), a subanat...

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Detalles Bibliográficos
Autores principales: Moeller, Tyler D., Shah, Shivem B., Lai, Kristine, Lopez-Barbosa, Natalia, Desai, Primit, Wang, Weiyao, Zhong, Zhe, Redmond, David, Singh, Ankur, DeLisa, Matthew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141597/
https://www.ncbi.nlm.nih.gov/pubmed/37122450
http://dx.doi.org/10.1021/acscentsci.2c01473

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