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Botulinum Toxin Type A for the Treatment of Auriculotemporal Neuralgia—A Case Series

Auriculotemporal neuralgia is a rare pain disorder in which anesthetic nerve blockade is usually effective but not always resolutive. Botulinum toxin type A has proven to be effective in treating neuropathic pain, and patients with auriculotemporal neuralgia could also benefit from this treatment. W...

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Autores principales: Tereshko, Yan, Belgrado, Enrico, Lettieri, Christian, Gigli, Gian Luigi, Valente, Mariarosaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141838/
https://www.ncbi.nlm.nih.gov/pubmed/37104212
http://dx.doi.org/10.3390/toxins15040274
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author Tereshko, Yan
Belgrado, Enrico
Lettieri, Christian
Gigli, Gian Luigi
Valente, Mariarosaria
author_facet Tereshko, Yan
Belgrado, Enrico
Lettieri, Christian
Gigli, Gian Luigi
Valente, Mariarosaria
author_sort Tereshko, Yan
collection PubMed
description Auriculotemporal neuralgia is a rare pain disorder in which anesthetic nerve blockade is usually effective but not always resolutive. Botulinum toxin type A has proven to be effective in treating neuropathic pain, and patients with auriculotemporal neuralgia could also benefit from this treatment. We described nine patients with auriculotemporal neuralgia treated with botulinum toxin type A in the territory of auriculotemporal nerve innervation. We compared the basal NRS and Penn facial pain scale scores with those obtained 1 month after BoNT/A injections. Both Penn facial pain scale (96.67 ± 24.61 vs. 45.11 ± 36.70, p 0.004; mean reduction 52.57 ± 36.50) and NRS scores (8.11 ± 1.27 vs. 4.22 ± 2.95, p 0.009; mean reduction 3.89 ± 2.52) improved significantly at one month after treatment. The mean duration of the effect of BoNT/A on pain was 95.00 ± 53.03 days and no adverse effects were reported.
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spelling pubmed-101418382023-04-29 Botulinum Toxin Type A for the Treatment of Auriculotemporal Neuralgia—A Case Series Tereshko, Yan Belgrado, Enrico Lettieri, Christian Gigli, Gian Luigi Valente, Mariarosaria Toxins (Basel) Article Auriculotemporal neuralgia is a rare pain disorder in which anesthetic nerve blockade is usually effective but not always resolutive. Botulinum toxin type A has proven to be effective in treating neuropathic pain, and patients with auriculotemporal neuralgia could also benefit from this treatment. We described nine patients with auriculotemporal neuralgia treated with botulinum toxin type A in the territory of auriculotemporal nerve innervation. We compared the basal NRS and Penn facial pain scale scores with those obtained 1 month after BoNT/A injections. Both Penn facial pain scale (96.67 ± 24.61 vs. 45.11 ± 36.70, p 0.004; mean reduction 52.57 ± 36.50) and NRS scores (8.11 ± 1.27 vs. 4.22 ± 2.95, p 0.009; mean reduction 3.89 ± 2.52) improved significantly at one month after treatment. The mean duration of the effect of BoNT/A on pain was 95.00 ± 53.03 days and no adverse effects were reported. MDPI 2023-04-06 /pmc/articles/PMC10141838/ /pubmed/37104212 http://dx.doi.org/10.3390/toxins15040274 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Tereshko, Yan
Belgrado, Enrico
Lettieri, Christian
Gigli, Gian Luigi
Valente, Mariarosaria
Botulinum Toxin Type A for the Treatment of Auriculotemporal Neuralgia—A Case Series
title Botulinum Toxin Type A for the Treatment of Auriculotemporal Neuralgia—A Case Series
title_full Botulinum Toxin Type A for the Treatment of Auriculotemporal Neuralgia—A Case Series
title_fullStr Botulinum Toxin Type A for the Treatment of Auriculotemporal Neuralgia—A Case Series
title_full_unstemmed Botulinum Toxin Type A for the Treatment of Auriculotemporal Neuralgia—A Case Series
title_short Botulinum Toxin Type A for the Treatment of Auriculotemporal Neuralgia—A Case Series
title_sort botulinum toxin type a for the treatment of auriculotemporal neuralgia—a case series
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141838/
https://www.ncbi.nlm.nih.gov/pubmed/37104212
http://dx.doi.org/10.3390/toxins15040274
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