Sickle Cell Hemoglobin Genotypes Affect Malaria Parasite Growth and Correlate with Exosomal miR-451a and let-7i-5p Levels

Malaria affects a significant portion of the global population, with 247 million cases in 2021, primarily in Africa. However, certain hemoglobinopathies, such as sickle cell trait (SCT), have been linked to lower mortality rates in malaria patients. Hemoglobin (Hb) mutations, including HbS and HbC,...

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Autores principales: Oxendine Harp, Keri, Bashi, Alaijah, Botchway, Felix, Addo-Gyan, Daniel, Tetteh-Tsifoanya, Mark, Lamptey, Amanda, Djameh, Georgina, Iqbal, Shareen A., Lekpor, Cecilia, Banerjee, Saswati, Wilson, Michael D., Dei-Adomakoh, Yvonne, Adjei, Andrew A., Stiles, Jonathan K., Driss, Adel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141851/
https://www.ncbi.nlm.nih.gov/pubmed/37108709
http://dx.doi.org/10.3390/ijms24087546

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