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Kinetically and thermodynamically controlled one-pot growth of gold nanoshells with NIR-II absorption for multimodal imaging-guided photothermal therapy
Since the successful clinical trial of AuroShell for photothermal therapy, there is currently intense interest in developing gold-based core-shell structures with near-infrared (NIR) absorption ranging from NIR-I (650–900 nm) to NIR-II (900–1700 nm). Here, we propose a seed-mediated successive growt...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141956/ https://www.ncbi.nlm.nih.gov/pubmed/37106405 http://dx.doi.org/10.1186/s12951-023-01907-1 |
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author | Chen, Ming Chen, Xiao-Tong Zhang, Lian-Ying Meng, Wei Chen, Yong-Jian Zhang, Ying-Shan Chen, Zhi-Cong Wang, Hui-Min Luo, Chun-Mei Shi, Xiu-Dong Zhang, Wen-Hua Wang, Mao-Sheng Chen, Jin-Xiang |
author_facet | Chen, Ming Chen, Xiao-Tong Zhang, Lian-Ying Meng, Wei Chen, Yong-Jian Zhang, Ying-Shan Chen, Zhi-Cong Wang, Hui-Min Luo, Chun-Mei Shi, Xiu-Dong Zhang, Wen-Hua Wang, Mao-Sheng Chen, Jin-Xiang |
author_sort | Chen, Ming |
collection | PubMed |
description | Since the successful clinical trial of AuroShell for photothermal therapy, there is currently intense interest in developing gold-based core-shell structures with near-infrared (NIR) absorption ranging from NIR-I (650–900 nm) to NIR-II (900–1700 nm). Here, we propose a seed-mediated successive growth approach to produce gold nanoshells on the surface of the nanoscale metal–organic framework (NMOF) of UiO-66-NH(2) (UiO = the University of Oslo) in one pot. The key to this strategy is to modulate the proportion of the formaldehyde (reductant) and its regulator / oxidative product of formic acid to harness the particle nucleation and growth rate within the same system. The gold nanoshells propagate through a well-oriented and controllable diffusion growth pattern (points → facets → octahedron), which has not been identified. Most strikingly, the gold nanoshells prepared hereby exhibit an exceedingly broad and strong absorption in NIR-II with a peak beyond 1300 nm and outstanding photothermal conversion efficiency of 74.0%. Owing to such superior performance, these gold nanoshells show promising outcomes in photoacoustic (PA), computed tomography (CT), and photothermal imaging-guided photothermal therapy (PTT) for breast cancer, as demonstrated both in vitro and in vivo. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12951-023-01907-1. |
format | Online Article Text |
id | pubmed-10141956 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-101419562023-04-29 Kinetically and thermodynamically controlled one-pot growth of gold nanoshells with NIR-II absorption for multimodal imaging-guided photothermal therapy Chen, Ming Chen, Xiao-Tong Zhang, Lian-Ying Meng, Wei Chen, Yong-Jian Zhang, Ying-Shan Chen, Zhi-Cong Wang, Hui-Min Luo, Chun-Mei Shi, Xiu-Dong Zhang, Wen-Hua Wang, Mao-Sheng Chen, Jin-Xiang J Nanobiotechnology Research Since the successful clinical trial of AuroShell for photothermal therapy, there is currently intense interest in developing gold-based core-shell structures with near-infrared (NIR) absorption ranging from NIR-I (650–900 nm) to NIR-II (900–1700 nm). Here, we propose a seed-mediated successive growth approach to produce gold nanoshells on the surface of the nanoscale metal–organic framework (NMOF) of UiO-66-NH(2) (UiO = the University of Oslo) in one pot. The key to this strategy is to modulate the proportion of the formaldehyde (reductant) and its regulator / oxidative product of formic acid to harness the particle nucleation and growth rate within the same system. The gold nanoshells propagate through a well-oriented and controllable diffusion growth pattern (points → facets → octahedron), which has not been identified. Most strikingly, the gold nanoshells prepared hereby exhibit an exceedingly broad and strong absorption in NIR-II with a peak beyond 1300 nm and outstanding photothermal conversion efficiency of 74.0%. Owing to such superior performance, these gold nanoshells show promising outcomes in photoacoustic (PA), computed tomography (CT), and photothermal imaging-guided photothermal therapy (PTT) for breast cancer, as demonstrated both in vitro and in vivo. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12951-023-01907-1. BioMed Central 2023-04-28 /pmc/articles/PMC10141956/ /pubmed/37106405 http://dx.doi.org/10.1186/s12951-023-01907-1 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Chen, Ming Chen, Xiao-Tong Zhang, Lian-Ying Meng, Wei Chen, Yong-Jian Zhang, Ying-Shan Chen, Zhi-Cong Wang, Hui-Min Luo, Chun-Mei Shi, Xiu-Dong Zhang, Wen-Hua Wang, Mao-Sheng Chen, Jin-Xiang Kinetically and thermodynamically controlled one-pot growth of gold nanoshells with NIR-II absorption for multimodal imaging-guided photothermal therapy |
title | Kinetically and thermodynamically controlled one-pot growth of gold nanoshells with NIR-II absorption for multimodal imaging-guided photothermal therapy |
title_full | Kinetically and thermodynamically controlled one-pot growth of gold nanoshells with NIR-II absorption for multimodal imaging-guided photothermal therapy |
title_fullStr | Kinetically and thermodynamically controlled one-pot growth of gold nanoshells with NIR-II absorption for multimodal imaging-guided photothermal therapy |
title_full_unstemmed | Kinetically and thermodynamically controlled one-pot growth of gold nanoshells with NIR-II absorption for multimodal imaging-guided photothermal therapy |
title_short | Kinetically and thermodynamically controlled one-pot growth of gold nanoshells with NIR-II absorption for multimodal imaging-guided photothermal therapy |
title_sort | kinetically and thermodynamically controlled one-pot growth of gold nanoshells with nir-ii absorption for multimodal imaging-guided photothermal therapy |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141956/ https://www.ncbi.nlm.nih.gov/pubmed/37106405 http://dx.doi.org/10.1186/s12951-023-01907-1 |
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