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REAC Antalgic Neuro Modulation in Chronic Post Herpetic Neuralgia
Background: Chronic post-herpetic neuralgia (CPHN) is a symptomatic condition that afflicts adults and elderly individuals. The chronicity of this symptomatology can be conditioned by the epigenetic modifications induced by the virus on the processes of neurotransmission and sensitivity to pain. The...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141972/ https://www.ncbi.nlm.nih.gov/pubmed/37109039 http://dx.doi.org/10.3390/jpm13040653 |
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author | Barcessat, Ana Rita Pinheiro Nunes, Lucas dos Santos Gonçalves, Rebeca Góes Darienso, Danyela |
author_facet | Barcessat, Ana Rita Pinheiro Nunes, Lucas dos Santos Gonçalves, Rebeca Góes Darienso, Danyela |
author_sort | Barcessat, Ana Rita Pinheiro |
collection | PubMed |
description | Background: Chronic post-herpetic neuralgia (CPHN) is a symptomatic condition that afflicts adults and elderly individuals. The chronicity of this symptomatology can be conditioned by the epigenetic modifications induced by the virus on the processes of neurotransmission and sensitivity to pain. The aim of this study is to investigate whether manipulating endogenous bioelectrical activity (EBA), responsible for neurotransmission processes and contributing to the induction of epigenetic modifications, can alleviate pain symptoms. Methods: This manipulation was carried out with the antalgic neuromodulation (ANM) treatment of radioelectric asymmetric conveyer (REAC) technology. Pain assessment before and after treatment was performed using a numerical analog scale (NAS) and a simple descriptive scale (SDS). Results: The results of the analysis showed an over four-point decrease in NAS scale score and over one point decrease in SDS scale score, with a statistical significance for both tests of p < 0.005. Conclusions: The results obtained in this study demonstrate how REAC ANM manipulation of EBA can lead to improvement in epigenetically conditioned symptoms such as CPHN. These results should prompt further research to expand knowledge and ensure optimized therapeutic outcomes. |
format | Online Article Text |
id | pubmed-10141972 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-101419722023-04-29 REAC Antalgic Neuro Modulation in Chronic Post Herpetic Neuralgia Barcessat, Ana Rita Pinheiro Nunes, Lucas dos Santos Gonçalves, Rebeca Góes Darienso, Danyela J Pers Med Brief Report Background: Chronic post-herpetic neuralgia (CPHN) is a symptomatic condition that afflicts adults and elderly individuals. The chronicity of this symptomatology can be conditioned by the epigenetic modifications induced by the virus on the processes of neurotransmission and sensitivity to pain. The aim of this study is to investigate whether manipulating endogenous bioelectrical activity (EBA), responsible for neurotransmission processes and contributing to the induction of epigenetic modifications, can alleviate pain symptoms. Methods: This manipulation was carried out with the antalgic neuromodulation (ANM) treatment of radioelectric asymmetric conveyer (REAC) technology. Pain assessment before and after treatment was performed using a numerical analog scale (NAS) and a simple descriptive scale (SDS). Results: The results of the analysis showed an over four-point decrease in NAS scale score and over one point decrease in SDS scale score, with a statistical significance for both tests of p < 0.005. Conclusions: The results obtained in this study demonstrate how REAC ANM manipulation of EBA can lead to improvement in epigenetically conditioned symptoms such as CPHN. These results should prompt further research to expand knowledge and ensure optimized therapeutic outcomes. MDPI 2023-04-11 /pmc/articles/PMC10141972/ /pubmed/37109039 http://dx.doi.org/10.3390/jpm13040653 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Brief Report Barcessat, Ana Rita Pinheiro Nunes, Lucas dos Santos Gonçalves, Rebeca Góes Darienso, Danyela REAC Antalgic Neuro Modulation in Chronic Post Herpetic Neuralgia |
title | REAC Antalgic Neuro Modulation in Chronic Post Herpetic Neuralgia |
title_full | REAC Antalgic Neuro Modulation in Chronic Post Herpetic Neuralgia |
title_fullStr | REAC Antalgic Neuro Modulation in Chronic Post Herpetic Neuralgia |
title_full_unstemmed | REAC Antalgic Neuro Modulation in Chronic Post Herpetic Neuralgia |
title_short | REAC Antalgic Neuro Modulation in Chronic Post Herpetic Neuralgia |
title_sort | reac antalgic neuro modulation in chronic post herpetic neuralgia |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141972/ https://www.ncbi.nlm.nih.gov/pubmed/37109039 http://dx.doi.org/10.3390/jpm13040653 |
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