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Fifty-Five Years of Research on B, C and D in Escherichia coli

The basic properties of the Escherichia coli duplication process can be defined by two time periods: C, the time for a round of chromosome replication, and D, the time between the end of a round of replication and cell division. Given the durations of these periods, the pattern of chromosome replica...

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Detalles Bibliográficos
Autor principal: Helmstetter, Charles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141973/
https://www.ncbi.nlm.nih.gov/pubmed/37109506
http://dx.doi.org/10.3390/life13040977
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author Helmstetter, Charles E.
author_facet Helmstetter, Charles E.
author_sort Helmstetter, Charles E.
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description The basic properties of the Escherichia coli duplication process can be defined by two time periods: C, the time for a round of chromosome replication, and D, the time between the end of a round of replication and cell division. Given the durations of these periods, the pattern of chromosome replication during the cell cycle can be determined for cells growing with any doubling time. In the 55 years since these parameters were identified, there have been numerous investigations into their durations and into the elements that determine their initiations. In this review, I discuss the history of our involvement in these studies from the very beginning, some of what has been learned over the years by measuring the durations of C and D, and what might be learned with additional investigations.
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spelling pubmed-101419732023-04-29 Fifty-Five Years of Research on B, C and D in Escherichia coli Helmstetter, Charles E. Life (Basel) Review The basic properties of the Escherichia coli duplication process can be defined by two time periods: C, the time for a round of chromosome replication, and D, the time between the end of a round of replication and cell division. Given the durations of these periods, the pattern of chromosome replication during the cell cycle can be determined for cells growing with any doubling time. In the 55 years since these parameters were identified, there have been numerous investigations into their durations and into the elements that determine their initiations. In this review, I discuss the history of our involvement in these studies from the very beginning, some of what has been learned over the years by measuring the durations of C and D, and what might be learned with additional investigations. MDPI 2023-04-10 /pmc/articles/PMC10141973/ /pubmed/37109506 http://dx.doi.org/10.3390/life13040977 Text en © 2023 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Helmstetter, Charles E.
Fifty-Five Years of Research on B, C and D in Escherichia coli
title Fifty-Five Years of Research on B, C and D in Escherichia coli
title_full Fifty-Five Years of Research on B, C and D in Escherichia coli
title_fullStr Fifty-Five Years of Research on B, C and D in Escherichia coli
title_full_unstemmed Fifty-Five Years of Research on B, C and D in Escherichia coli
title_short Fifty-Five Years of Research on B, C and D in Escherichia coli
title_sort fifty-five years of research on b, c and d in escherichia coli
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10141973/
https://www.ncbi.nlm.nih.gov/pubmed/37109506
http://dx.doi.org/10.3390/life13040977
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