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Quadrivalent Formulation of Intranasal Influenza Vaccine M2SR (M2-Deficient Single Replication) Protects against Drifted Influenza A and B Virus Challenge

Current influenza vaccines demonstrate low vaccine efficacy, especially when the predominantly circulating strain and vaccine are mismatched. The novel influenza vaccine platform M2- or BM2-deficient single replication (M2SR and BM2SR) has been shown to safely induce strong systemic and mucosal anti...

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Detalles Bibliográficos
Autores principales: Hill-Batorski, Lindsay, Hatta, Yasuko, Moser, Michael J., Sarawar, Sally, Neumann, Gabriele, Kawaoka, Yoshihiro, Bilsel, Pamuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142185/
https://www.ncbi.nlm.nih.gov/pubmed/37112710
http://dx.doi.org/10.3390/vaccines11040798