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Increasing temperature denatures canine IgG reducing its ability to inhibit heartworm antigen detection

BACKGROUND: Immune complexing of target antigen to high affinity host antibody is recognized to impact the sensitivity of commercial heartworm antigen tests. Published information describing the effect of heat on interfering canine host antibodies is lacking. Immune complex dissociation (ICD) by hea...

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Detalles Bibliográficos
Autores principales:	Gruntmeir, Jeff M., Abbott, Jeff R., Kima, Peter E., Long, Maureen T., Blagburn, Byron L., Walden, Heather S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142223/ https://www.ncbi.nlm.nih.gov/pubmed/37106356 http://dx.doi.org/10.1186/s13071-023-05739-8

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