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An Updated Review on the Multifaceted Therapeutic Potential of Calendula officinalis L.

Calendula officinalis Linn. (CO) is a popular medicinal plant from the plant kingdom’s Asteraceae family that has been used for millennia. This plant contains flavonoids, triterpenoids, glycosides, saponins, carotenoids, volatile oil, amino acids, steroids, sterols, and quinines. These chemical cons...

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Autores principales: Shahane, Kiran, Kshirsagar, Madhuri, Tambe, Srushti, Jain, Divya, Rout, Srutee, Ferreira, Maria Karolina Martins, Mali, Suraj, Amin, Purnima, Srivastav, Prem Prakash, Cruz, Jorddy, Lima, Rafael Rodrigues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142266/
https://www.ncbi.nlm.nih.gov/pubmed/37111369
http://dx.doi.org/10.3390/ph16040611
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author Shahane, Kiran
Kshirsagar, Madhuri
Tambe, Srushti
Jain, Divya
Rout, Srutee
Ferreira, Maria Karolina Martins
Mali, Suraj
Amin, Purnima
Srivastav, Prem Prakash
Cruz, Jorddy
Lima, Rafael Rodrigues
author_facet Shahane, Kiran
Kshirsagar, Madhuri
Tambe, Srushti
Jain, Divya
Rout, Srutee
Ferreira, Maria Karolina Martins
Mali, Suraj
Amin, Purnima
Srivastav, Prem Prakash
Cruz, Jorddy
Lima, Rafael Rodrigues
author_sort Shahane, Kiran
collection PubMed
description Calendula officinalis Linn. (CO) is a popular medicinal plant from the plant kingdom’s Asteraceae family that has been used for millennia. This plant contains flavonoids, triterpenoids, glycosides, saponins, carotenoids, volatile oil, amino acids, steroids, sterols, and quinines. These chemical constituents confer multifaceted biological effects such as anti-inflammatory, anti-cancer, antihelminthic, antidiabetes, wound healing, hepatoprotective, and antioxidant activities. Additionally, it is employed in cases of certain burns and gastrointestinal, gynecological, ocular, and skin conditions. In this review, we have discussed recent research from the last five years on the therapeutic applications of CO and emphasized its myriad capabilities as a traditional medicine. We have also elucidated CO’s molecular mechanisms and recent clinical studies. Overall, this review intends to summarize, fill in the gaps in the existing research, and provide a wealth of possibilities for researchers working to validate traditional claims and advance the safe and effective use of CO in treating various ailments.
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spelling pubmed-101422662023-04-29 An Updated Review on the Multifaceted Therapeutic Potential of Calendula officinalis L. Shahane, Kiran Kshirsagar, Madhuri Tambe, Srushti Jain, Divya Rout, Srutee Ferreira, Maria Karolina Martins Mali, Suraj Amin, Purnima Srivastav, Prem Prakash Cruz, Jorddy Lima, Rafael Rodrigues Pharmaceuticals (Basel) Review Calendula officinalis Linn. (CO) is a popular medicinal plant from the plant kingdom’s Asteraceae family that has been used for millennia. This plant contains flavonoids, triterpenoids, glycosides, saponins, carotenoids, volatile oil, amino acids, steroids, sterols, and quinines. These chemical constituents confer multifaceted biological effects such as anti-inflammatory, anti-cancer, antihelminthic, antidiabetes, wound healing, hepatoprotective, and antioxidant activities. Additionally, it is employed in cases of certain burns and gastrointestinal, gynecological, ocular, and skin conditions. In this review, we have discussed recent research from the last five years on the therapeutic applications of CO and emphasized its myriad capabilities as a traditional medicine. We have also elucidated CO’s molecular mechanisms and recent clinical studies. Overall, this review intends to summarize, fill in the gaps in the existing research, and provide a wealth of possibilities for researchers working to validate traditional claims and advance the safe and effective use of CO in treating various ailments. MDPI 2023-04-18 /pmc/articles/PMC10142266/ /pubmed/37111369 http://dx.doi.org/10.3390/ph16040611 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Shahane, Kiran
Kshirsagar, Madhuri
Tambe, Srushti
Jain, Divya
Rout, Srutee
Ferreira, Maria Karolina Martins
Mali, Suraj
Amin, Purnima
Srivastav, Prem Prakash
Cruz, Jorddy
Lima, Rafael Rodrigues
An Updated Review on the Multifaceted Therapeutic Potential of Calendula officinalis L.
title An Updated Review on the Multifaceted Therapeutic Potential of Calendula officinalis L.
title_full An Updated Review on the Multifaceted Therapeutic Potential of Calendula officinalis L.
title_fullStr An Updated Review on the Multifaceted Therapeutic Potential of Calendula officinalis L.
title_full_unstemmed An Updated Review on the Multifaceted Therapeutic Potential of Calendula officinalis L.
title_short An Updated Review on the Multifaceted Therapeutic Potential of Calendula officinalis L.
title_sort updated review on the multifaceted therapeutic potential of calendula officinalis l.
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142266/
https://www.ncbi.nlm.nih.gov/pubmed/37111369
http://dx.doi.org/10.3390/ph16040611
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