Cargando…
An Updated Review on the Multifaceted Therapeutic Potential of Calendula officinalis L.
Calendula officinalis Linn. (CO) is a popular medicinal plant from the plant kingdom’s Asteraceae family that has been used for millennia. This plant contains flavonoids, triterpenoids, glycosides, saponins, carotenoids, volatile oil, amino acids, steroids, sterols, and quinines. These chemical cons...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142266/ https://www.ncbi.nlm.nih.gov/pubmed/37111369 http://dx.doi.org/10.3390/ph16040611 |
_version_ | 1785033572236656640 |
---|---|
author | Shahane, Kiran Kshirsagar, Madhuri Tambe, Srushti Jain, Divya Rout, Srutee Ferreira, Maria Karolina Martins Mali, Suraj Amin, Purnima Srivastav, Prem Prakash Cruz, Jorddy Lima, Rafael Rodrigues |
author_facet | Shahane, Kiran Kshirsagar, Madhuri Tambe, Srushti Jain, Divya Rout, Srutee Ferreira, Maria Karolina Martins Mali, Suraj Amin, Purnima Srivastav, Prem Prakash Cruz, Jorddy Lima, Rafael Rodrigues |
author_sort | Shahane, Kiran |
collection | PubMed |
description | Calendula officinalis Linn. (CO) is a popular medicinal plant from the plant kingdom’s Asteraceae family that has been used for millennia. This plant contains flavonoids, triterpenoids, glycosides, saponins, carotenoids, volatile oil, amino acids, steroids, sterols, and quinines. These chemical constituents confer multifaceted biological effects such as anti-inflammatory, anti-cancer, antihelminthic, antidiabetes, wound healing, hepatoprotective, and antioxidant activities. Additionally, it is employed in cases of certain burns and gastrointestinal, gynecological, ocular, and skin conditions. In this review, we have discussed recent research from the last five years on the therapeutic applications of CO and emphasized its myriad capabilities as a traditional medicine. We have also elucidated CO’s molecular mechanisms and recent clinical studies. Overall, this review intends to summarize, fill in the gaps in the existing research, and provide a wealth of possibilities for researchers working to validate traditional claims and advance the safe and effective use of CO in treating various ailments. |
format | Online Article Text |
id | pubmed-10142266 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-101422662023-04-29 An Updated Review on the Multifaceted Therapeutic Potential of Calendula officinalis L. Shahane, Kiran Kshirsagar, Madhuri Tambe, Srushti Jain, Divya Rout, Srutee Ferreira, Maria Karolina Martins Mali, Suraj Amin, Purnima Srivastav, Prem Prakash Cruz, Jorddy Lima, Rafael Rodrigues Pharmaceuticals (Basel) Review Calendula officinalis Linn. (CO) is a popular medicinal plant from the plant kingdom’s Asteraceae family that has been used for millennia. This plant contains flavonoids, triterpenoids, glycosides, saponins, carotenoids, volatile oil, amino acids, steroids, sterols, and quinines. These chemical constituents confer multifaceted biological effects such as anti-inflammatory, anti-cancer, antihelminthic, antidiabetes, wound healing, hepatoprotective, and antioxidant activities. Additionally, it is employed in cases of certain burns and gastrointestinal, gynecological, ocular, and skin conditions. In this review, we have discussed recent research from the last five years on the therapeutic applications of CO and emphasized its myriad capabilities as a traditional medicine. We have also elucidated CO’s molecular mechanisms and recent clinical studies. Overall, this review intends to summarize, fill in the gaps in the existing research, and provide a wealth of possibilities for researchers working to validate traditional claims and advance the safe and effective use of CO in treating various ailments. MDPI 2023-04-18 /pmc/articles/PMC10142266/ /pubmed/37111369 http://dx.doi.org/10.3390/ph16040611 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Shahane, Kiran Kshirsagar, Madhuri Tambe, Srushti Jain, Divya Rout, Srutee Ferreira, Maria Karolina Martins Mali, Suraj Amin, Purnima Srivastav, Prem Prakash Cruz, Jorddy Lima, Rafael Rodrigues An Updated Review on the Multifaceted Therapeutic Potential of Calendula officinalis L. |
title | An Updated Review on the Multifaceted Therapeutic Potential of Calendula officinalis L. |
title_full | An Updated Review on the Multifaceted Therapeutic Potential of Calendula officinalis L. |
title_fullStr | An Updated Review on the Multifaceted Therapeutic Potential of Calendula officinalis L. |
title_full_unstemmed | An Updated Review on the Multifaceted Therapeutic Potential of Calendula officinalis L. |
title_short | An Updated Review on the Multifaceted Therapeutic Potential of Calendula officinalis L. |
title_sort | updated review on the multifaceted therapeutic potential of calendula officinalis l. |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142266/ https://www.ncbi.nlm.nih.gov/pubmed/37111369 http://dx.doi.org/10.3390/ph16040611 |
work_keys_str_mv | AT shahanekiran anupdatedreviewonthemultifacetedtherapeuticpotentialofcalendulaofficinalisl AT kshirsagarmadhuri anupdatedreviewonthemultifacetedtherapeuticpotentialofcalendulaofficinalisl AT tambesrushti anupdatedreviewonthemultifacetedtherapeuticpotentialofcalendulaofficinalisl AT jaindivya anupdatedreviewonthemultifacetedtherapeuticpotentialofcalendulaofficinalisl AT routsrutee anupdatedreviewonthemultifacetedtherapeuticpotentialofcalendulaofficinalisl AT ferreiramariakarolinamartins anupdatedreviewonthemultifacetedtherapeuticpotentialofcalendulaofficinalisl AT malisuraj anupdatedreviewonthemultifacetedtherapeuticpotentialofcalendulaofficinalisl AT aminpurnima anupdatedreviewonthemultifacetedtherapeuticpotentialofcalendulaofficinalisl AT srivastavpremprakash anupdatedreviewonthemultifacetedtherapeuticpotentialofcalendulaofficinalisl AT cruzjorddy anupdatedreviewonthemultifacetedtherapeuticpotentialofcalendulaofficinalisl AT limarafaelrodrigues anupdatedreviewonthemultifacetedtherapeuticpotentialofcalendulaofficinalisl AT shahanekiran updatedreviewonthemultifacetedtherapeuticpotentialofcalendulaofficinalisl AT kshirsagarmadhuri updatedreviewonthemultifacetedtherapeuticpotentialofcalendulaofficinalisl AT tambesrushti updatedreviewonthemultifacetedtherapeuticpotentialofcalendulaofficinalisl AT jaindivya updatedreviewonthemultifacetedtherapeuticpotentialofcalendulaofficinalisl AT routsrutee updatedreviewonthemultifacetedtherapeuticpotentialofcalendulaofficinalisl AT ferreiramariakarolinamartins updatedreviewonthemultifacetedtherapeuticpotentialofcalendulaofficinalisl AT malisuraj updatedreviewonthemultifacetedtherapeuticpotentialofcalendulaofficinalisl AT aminpurnima updatedreviewonthemultifacetedtherapeuticpotentialofcalendulaofficinalisl AT srivastavpremprakash updatedreviewonthemultifacetedtherapeuticpotentialofcalendulaofficinalisl AT cruzjorddy updatedreviewonthemultifacetedtherapeuticpotentialofcalendulaofficinalisl AT limarafaelrodrigues updatedreviewonthemultifacetedtherapeuticpotentialofcalendulaofficinalisl |