A Novel Derivative of Curcumol, HCL-23, Inhibits the Malignant Phenotype of Triple-Negative Breast Cancer and Induces Apoptosis and HO-1-Dependent Ferroptosis

Triple-negative breast cancer (TNBC) is the most aggressive molecular subtype of breast cancer. Curcumol, as a natural small molecule compound, has potential anti-breast cancer activity. In this study, we chemically synthesized a derivative of curcumol, named HCL-23, by structural modification and e...

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Detalles Bibliográficos
Autores principales: Zhao, Peng, Song, Hui, Gao, Futian, Chen, Liang, Qiu, Jianfei, Jin, Jun, Pan, Chaolan, Tang, Yunyan, Chen, Meijun, Pan, Yang, Li, Yanmei, Huang, Liejun, Yang, Jue, Hao, Xiaojiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142363/
https://www.ncbi.nlm.nih.gov/pubmed/37110625
http://dx.doi.org/10.3390/molecules28083389

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