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mTOR Inhibition Impairs the Activation and Function of Belatacept-Resistant CD4(+)CD57(+) T Cells In Vivo and In Vitro

Calcineurin inhibitors have improved graft survival in solid-organ transplantation but their use is limited by toxicity, requiring a switch to another immunosuppressor in some cases. Belatacept is one option that has been shown to improve graft and patient survival despite being associated with a hi...

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Detalles Bibliográficos
Autores principales:	Herr, Florence, Dekeyser, Manon, Le Pavec, Jerome, Desterke, Christophe, Chiron, Andrada-Silvana, Bargiel, Karen, Mercier, Olaf, Vernochet, Amelia, Fadel, Elie, Durrbach, Antoine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142381/ https://www.ncbi.nlm.nih.gov/pubmed/37111784 http://dx.doi.org/10.3390/pharmaceutics15041299

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