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Trends in Availability of Genetic Tests in the United States, 2012–2022

Globally, genetic testing has become increasingly used over the last two decades. As a result of the rapid development of genetic tests, the Genetic Testing Registry was created in the United States to provide transparent information on genetic tests and the corresponding laboratories. Using publicl...

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Autores principales: Halbisen, Alyssa L., Lu, Christine Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142561/
https://www.ncbi.nlm.nih.gov/pubmed/37109024
http://dx.doi.org/10.3390/jpm13040638
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author Halbisen, Alyssa L.
Lu, Christine Y.
author_facet Halbisen, Alyssa L.
Lu, Christine Y.
author_sort Halbisen, Alyssa L.
collection PubMed
description Globally, genetic testing has become increasingly used over the last two decades. As a result of the rapid development of genetic tests, the Genetic Testing Registry was created in the United States to provide transparent information on genetic tests and the corresponding laboratories. Using publicly available data from the Genetic Testing Registry, we analyzed trends in the availability of genetic tests in the United States over the last decade. As of November 2022, a total of 129,624 and 197,779 genetic tests in the US and globally, respectively, including updated versions of previously existing tests, have been made available and submitted to the genetic testing registry. Over 90% of tests submitted to GTR are for clinical rather than research purposes. Worldwide, 1081 and 6214 new genetic tests had been made available in 2012 and in 2022, respectively. In 2012, only 607 and in 2022, 3097 new genetic tests were made available in the US, with 2016 seeing the biggest increase in availability of new tests during the study period. Over 90% of tests can be used for diagnosis. In the US, 10 of >250 laboratories account for 81% of new genetic tests in GTR. As more genetic tests become available, further international collaboration is required for a comprehensive understanding of the available genetic tests worldwide.
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spelling pubmed-101425612023-04-29 Trends in Availability of Genetic Tests in the United States, 2012–2022 Halbisen, Alyssa L. Lu, Christine Y. J Pers Med Communication Globally, genetic testing has become increasingly used over the last two decades. As a result of the rapid development of genetic tests, the Genetic Testing Registry was created in the United States to provide transparent information on genetic tests and the corresponding laboratories. Using publicly available data from the Genetic Testing Registry, we analyzed trends in the availability of genetic tests in the United States over the last decade. As of November 2022, a total of 129,624 and 197,779 genetic tests in the US and globally, respectively, including updated versions of previously existing tests, have been made available and submitted to the genetic testing registry. Over 90% of tests submitted to GTR are for clinical rather than research purposes. Worldwide, 1081 and 6214 new genetic tests had been made available in 2012 and in 2022, respectively. In 2012, only 607 and in 2022, 3097 new genetic tests were made available in the US, with 2016 seeing the biggest increase in availability of new tests during the study period. Over 90% of tests can be used for diagnosis. In the US, 10 of >250 laboratories account for 81% of new genetic tests in GTR. As more genetic tests become available, further international collaboration is required for a comprehensive understanding of the available genetic tests worldwide. MDPI 2023-04-06 /pmc/articles/PMC10142561/ /pubmed/37109024 http://dx.doi.org/10.3390/jpm13040638 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Halbisen, Alyssa L.
Lu, Christine Y.
Trends in Availability of Genetic Tests in the United States, 2012–2022
title Trends in Availability of Genetic Tests in the United States, 2012–2022
title_full Trends in Availability of Genetic Tests in the United States, 2012–2022
title_fullStr Trends in Availability of Genetic Tests in the United States, 2012–2022
title_full_unstemmed Trends in Availability of Genetic Tests in the United States, 2012–2022
title_short Trends in Availability of Genetic Tests in the United States, 2012–2022
title_sort trends in availability of genetic tests in the united states, 2012–2022
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142561/
https://www.ncbi.nlm.nih.gov/pubmed/37109024
http://dx.doi.org/10.3390/jpm13040638
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