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Formulation and Characterization of Epalrestat-Loaded Polysorbate 60 Cationic Niosomes for Ocular Delivery

The aim of this work was to develop niosomes for the ocular delivery of epalrestat, a drug that inhibits the polyol pathway and protects diabetic eyes from damage linked to sorbitol production and accumulation. Cationic niosomes were made using polysorbate 60, cholesterol, and 1,2-di-O-octadecenyl-3...

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Detalles Bibliográficos
Autores principales: Kattar, Axel, Quelle-Regaldie, Ana, Sánchez, Laura, Concheiro, Angel, Alvarez-Lorenzo, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142600/
https://www.ncbi.nlm.nih.gov/pubmed/37111732
http://dx.doi.org/10.3390/pharmaceutics15041247