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Colitis fulminante por Clostridium Difficile en paciente con antecedentes de trasplante de hígado: una complicación potencialmente mortal.

Clostridiodes difficile's fulminant colitis is characterized by the development of severe acute inflammation of the colon, associated with systemic toxicity. Fulminant colitis is a serious form of acute colitis with a mortality of up to 80%. We present the case of a 45-year-old man who presente...

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Detalles Bibliográficos
Autores principales: Sultano, Nicolas, Gonzalez Salazar, Esteban, Poggi, Catalina, Higuera, Felipe, Pekolj, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Universidad Nacional de Córdoba 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142679/
https://www.ncbi.nlm.nih.gov/pubmed/37018358
http://dx.doi.org/10.31053/1853.0605.v80.n1.37579
Descripción
Sumario:Clostridiodes difficile's fulminant colitis is characterized by the development of severe acute inflammation of the colon, associated with systemic toxicity. Fulminant colitis is a serious form of acute colitis with a mortality of up to 80%. We present the case of a 45-year-old man who presented to the emergency department with acute abdominal pain, diarrhea and fever. Computed tomography showed circumferential diffuse parietal thickening of the colon, including the rectum, associated with striation of the surrounding tissues and ganglionic formations. In the following hours the patient evolved with worsening of the general condition, increased inotropic requirements and lactic acidosis. Emergency laparotomy was decided and total colectomy was performed. Fulminant Clostridiodes difficile colitis is a potentially deadly disease. The lability of the pathology in many occasions forces quick decision making, therefore fulminant colitis represents a medical surgical emergency being time crucial.