Betulinic Acid-Brosimine B Hybrid Compound Has a Synergistic Effect with Imatinib in Chronic Myeloid Leukemia Cell Line, Modulating Apoptosis and Autophagy

Chronic myeloid leukemia (CML) is a myeloproliferative disease characterized by the formation of the BCR-ABL (breakpoint cluster region-Abelson) oncoprotein. As many patients display therapeutic resistance, the development of new drugs based on semisynthetic products represents a new potential thera...

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Detalles Bibliográficos
Autores principales: Willig, Julia Biz, de Couto, Nádia Miléo Garcês, Vianna, Débora Renz Barreto, Mariot, Camila da Silveira, Gnoatto, Simone Cristina Baggio, Buffon, Andréia, Pilger, Diogo André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142704/
https://www.ncbi.nlm.nih.gov/pubmed/37111343
http://dx.doi.org/10.3390/ph16040586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10142704/
https://www.ncbi.nlm.nih.gov/pubmed/37111343
http://dx.doi.org/10.3390/ph16040586

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